Q.Which of the following cells are responsible for humoral immune response?
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🔒 Start your 14-day free trial to unlock the full solution →Concept understanding — Cell-Mediated and Humoral Immunity
These are the two mechanistic arms of acquired immunity. Cell-mediated immunity (CMI) destroys pathogens through the direct action of cells — T cells, macrophages and natural killer cells — without producing antibodies; it is especially important against intracellular pathogens and abnormal (e.g. cancerous or virus-infected) cells. Antibody-mediated or humoral immunity instead relies on B cells, which, with assistance from antigen-presenting cells and T-helper cells, differentiate into plasma cells that secrete antibodies to neutralise pathogens cir …
Acquired immunity has two separate arms — one built around circulating antibodies and another built around cells that act directly — and each is carried out by a different kind of lymphocyte. …
B-lymphocytes produce antibodies and mediate the humoral immune response; T-lymphocytes handle cell-mediated immunity.
Acquired immunity has two arms. In the humoral immune response (also called antibody-mediated immune response, AMIR), B-lymphocytes produce antibodies (proteins) that circulate in the blood plasma ('humor') and fight pathogens. In contrast, T-lymph …
- CBSE 2026Set A1 markMCQQ.Which of the following cells are responsible for humoral immune response?(a) B-lymphocytes(b) T-lymphocytes(c) Killer lymphocytes(d) Macrophages
›Reveal solutionSolution
B-lymphocytes produce antibodies and mediate the humoral immune response; T-lymphocytes handle cell-mediated immunity.
Acquired immunity has two arms. In the humoral immune response (also called antibody-mediated immune response, AMIR), B-lymphocytes produce antibodies (proteins) that circulate in the blood plasma ('humor') and fight pathogens. In contrast, T-lymph …
- CBSE 2026Set ANNUAL1 markMCQQ.Antibodies are the proteins produced by B-Lymphocytes in response to a pathogen as immunity. Which of the following is responsible for cell mediated immunity?(a) B - Lymphocytes(b) T - Lymphocytes(c) N - K Cells(d) Phagocytes
›Reveal solutionSolution
T-Lymphocytes carry out cell-mediated immunity; B-Lymphocytes carry out antibody (humoral) immunity.
The adaptive immune system has two arms:
- Humoral immunity — carried out by B-Lymphocytes, which differentiate into plasma cells that secrete antibodies into blood/lymph to neutralise pathogens/toxins. …
- CBSE 2025Set ANNUAL1 markQ.Name the type of cells that produce antibodies.
›Reveal solutionSolution
Antibodies are produced by plasma cells, which arise when B-lymphocytes are activated by exposure to a specific antigen.
B-lymphocytes are the cells responsible for humoral immunity. When a B cell encounters and recognises an antigen (often with the help of helper T cells), it becomes activated and proliferates, differentiating into two main types of cells: plasma cells, which actively secrete large amounts of antibodies specific to that antigen, and memory B cells, which persist …
- CBSE 2024Set D1 markQ.Match the following and write the correct pair. Column 'A':(i) Structural genes(ii) T-Lymphocytes(iii) Competition(iv) PBR322(v) Corona radiata. Column 'B':(a) bone marrow(b) vectors(c) ovum(d) detrimental interaction(e) z, y and a(f) RBCs. Find the correct match for item(ii) 'T-Lymphocytes' from Column 'B'.
›Reveal solutionSolution
'T-Lymphocytes' pairs with option (a) 'bone marrow' — the site where these immune cells originate.
Lymphocytes, the key cells of the specific (adaptive) immune system, are of two main types — B-lymphocytes and T-lymphocytes. Both types originate from stem cells present in the bone marrow.
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- CBSE 2022Set ANNUAL1 markQ.Name the two major groups of cells required to attain immunity.
›Reveal solutionSolution
Immunity is mediated chiefly by two classes of lymphocytes — B-cells, responsible for antibody-mediated (humoral) immunity, and T-cells, responsible for cell-mediated immunity.
The adaptive immune system relies on two major populations of lymphocytes that mature in different primary lymphoid organs. B-lymphocytes mature in the bone marrow and, upon activation, differentiate into plasma cells that secrete antibodies, providing humoral (antibody-mediated) immunity. T-lymphocytes mature in the thymus and are responsible for cell-mediated immunity, which includes helper T-cells (that assist B- …
- CBSE 2019Set ANNUAL1 markMCQQ.An example for immunosuppressive drug is ________.(a) Anthromycin(b) Cyclosporin(c) Imidazole(d) Amantidine
›Reveal solutionSolution
Cyclosporin A is the classic immunosuppressive drug used to prevent transplant rejection.
Cyclosporin, originally isolated from the fungus Tolypocladium inflatum, blocks the activation of T-lymphocytes (by inhibiting calcineurin and IL-2 production), dampening the immune response that would otherwise attack a transplanted organ as foreign — this is why it is a mainstay of post-transplant therapy. Anthromycin and Amantadine are antimicrobial/antiviral agents, and Imidazole compounds are mai …
- CBSE 2016Set ANNUAL1 markMCQQ.Humoral immune response is performed by(a) Lymph nodes(b) B-lymphocyte(c) T-lymphocyte(d) Spleen
›Reveal solutionSolution
Humoral immunity is antibody-mediated; it is executed by B-lymphocytes, in contrast to cell-mediated immunity executed by T-lymphocytes.
The adaptive (acquired) immune response has two arms: humoral immunity (antibody-mediated immunity, AMI) and cell-mediated immunity (CMI). Humoral immunity is carried out by B-lymphocytes: when a B-cell encounters its specific antigen (with helper-T-cell assistance), it proliferates and differentiates into plasma cells that secrete large quantities of soluble antibodies into blood and lymph (the body's "humors" — hence the name); some B-cells become long-lived memory cells. These circulating antibodies neutralise or tag extracellular pathogens and toxins for destruction.
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