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Q.Describe about the exaggerated response of immune system to certain antigens present in the environment.

Gujarat GsebGSEB Higher Secondary Certificate (HSC) Examination 2023Subjective· 4mImportance★★★★★
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Allergy is an exaggerated (hypersensitive) immune reaction to harmless environmental antigens (allergens), mediated by IgE and the release of histamine.

Allergy:

  • Definition: the exaggerated response of the immune system to certain antigens present in the environment. The substances causing it are called allergens (e.g. house dust, dust mites, pollen, animal dander).
  • Mechanism: exposure to an allergen stimulates the production of IgE-type antibodies. These bind to mast cells and basophils. On re-exposure, the allergen cross-links the IgE, causing these cells to release chemical mediators - mainly histamine and serotonin.
  • Symptoms: sneezing, watery eyes, running nose, itching, and difficulty in breathing (as in asthma). …

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