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Q.

Some bioactive molecules, their source and their medical importance are given in the table below. Fill up the missing parts.

Bioactive MoleculeSourceMedical Importance
a____StreptococcusRemoves clots from blood vessels
Cyclosporin-Ab____c____
d____Monascus PurpureusBlood Cholesterol lowering agent
Kerala DhseKerala DHSE Plus Two Board 2013Subjective· 2mImportance★★★★★
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The table lists three microbial bioactive molecules used in medicine: Streptokinase from Streptococcus (clot buster), Cyclosporin-A from Trichoderma polysporum (immunosuppressant), and Statins from Monascus purpureus (cholesterol-lowering).

Bioactive MoleculeSourceMedical Importance
Streptokinase (a)StreptococcusRemoves clots from blood vessels
Cyclosporin-ATrichoderma polysporum (b)Used as an immunosuppressive agent, e.g. to prevent rejection in organ-transplant patients (c)
Statins, e.g. Lovastatin (d)Monascus purpureusBlood cholesterol lowering agent
  • a — Streptokinase: produced by the bacterium Streptococcus (and modified by genetic engineering), it is used clinically as a clot-buster to dissolve blood clots in patients who have suffered a myocardial infarction.
  • b — Trichoderma polysporum: the fungus from which Cyclosporin-A is obtained. …

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