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Q.What are the differences between Klinefelter's syndrome and Turner's syndrome in terms of their causes and karyotypes?

Manipur CohsemCOHSEM Manipur Higher Secondary Board 2026Subjective· 2mImportance★★★★★
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Klinefelter's = 47, XXY (extra X, affected male); Turner's = 45, X0 (missing X, affected female) — both due to non-disjunction of sex chromosomes.

Both conditions are examples of aneuploidy of the sex chromosomes, arising from non-disjunction during meiosis (gamete formation).

Klinefelter's syndrome:

  • Cause: presence of an additional X chromosome in a male.
  • Karyotype: 47, XXY (i.e. 44 autosomes + XXY).
  • Individual is a male but develops some feminine (gynaecomastia) features and is sterile.

Turner's syndrome:

  • Cause: absence (loss) of one X chromosome in a female. …

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