Chemistry · Class 12 Science
Ch 10Biomolecules — Class 12 Chemistry, concept-first.
Every living organism grows, maintains itself, and reproduces — yet at bottom it is built from the same non-living atoms and molecules that make up the rest of the physical world.
Key concepts
Hover a concept to preview it and jump to its most relevant Q&A.
Like Dissolves Like
Imagine you drop a spoonful of sugar into a glass of water. Stir once, and it disappears. Now try the same with a spoonful of sand. It just sits at the bottom.
Most relevant Q&A
Chapter contents
The NCERT structure, section by section. Open a section to see its questions, then read the concept-first solution.
Introduction
Every living organism grows, maintains itself, and reproduces — yet at bottom it is built from the same non-living atoms and molecules that make up the rest of the physical world.
Carbohydrates
Carbohydrates form one of the largest groups of naturally occurring organic compounds, and plants are their primary source. Everyday examples include cane sugar, glucose and starch.
Classification of Carbohydrates
Carbohydrates are sorted according to how they behave when hydrolysed — that is, by how many (if any) simpler sugar units they break down into on treatment with acid or water.
Monosaccharides
Within the monosaccharide group itself, a further split is made along two independent axes: how many carbon atoms the molecule has, and which carbonyl functional group it carries.
Glucose
Glucose is an aldohexose, and its everyday name in commerce and physiology is dextrose. It occurs freely in nature — sweet fruits, honey and ripe grapes are all rich in it — and also occurs in the com…
Fructose
Fructose is the second important hexose sugar of the chapter, and it is a ketohexose rather than an aldohexose.
Disaccharides
When a disaccharide is hydrolysed — using dilute acid or an appropriate enzyme — it splits into two monosaccharide units, which may be identical or different.
Polysaccharides
Polysaccharides are built from a very large number of monosaccharide units, all linked together by glycosidic linkages.
Importance of Carbohydrates
Carbohydrates are essential to life in both the plant and animal kingdoms, forming a major portion of the food that living organisms consume.
+−Intext Questions 10.1-10.3i3 questions
- 10.1Glucose or sucrose are soluble in water but cyclohexane or benzene (simple six membered ring compounds) are insoluble in water. Explain.Free
- 10.2What are the expected products of hydrolysis of lactose?Preview
- 10.3How do you explain the absence of aldehyde group in the pentaacetate of D-glucose?Preview
Proteins
Proteins are the single most abundant class of biomolecule in any living system. They are found in every tissue and every part of the body, and they underpin both the structure and the function of lif…
Amino Acids
An amino acid is any molecule carrying two functional groups at once: a basic amino group () and an acidic carboxyl group ().
Classification of Amino Acids
Beyond their individual side chains, amino acids can be grouped into three broad categories based on a simple count: how many amino groups versus how many carboxyl groups a given amino acid's structur…
Structure of Proteins
Proteins are polymers of α-amino acids, and the individual amino acid units are joined to each other through a peptide bond (also called a peptide linkage).
Denaturation of Proteins
A protein that exists in a biological system with its own unique three-dimensional structure and full biological activity is called a native protein.
Enzymes
A living organism survives because thousands of chemical reactions inside it run in a coordinated sequence — digesting food, absorbing the useful molecules, and finally releasing energy from them is o…
Mechanism of Enzyme Action
Because an enzyme acts as a catalyst and is not itself consumed in the reaction it speeds up, a reaction can be driven to completion using only a tiny quantity of the enzyme relative to the amount of…
Vitamins
Certain organic compounds are needed by the body only in very small quantities, yet their absence has a very specific consequence: a deficiency of one particular vitamin produces one particular diseas…
Classification of Vitamins
Vitamins are sorted into two broad groups purely on the basis of one physical property: whether they dissolve in water or in fat.
Nucleic Acids
Every organism resembles its parents and ancestors in many ways — this transmission of inherited characters from one generation to the next is called heredity.
Chemical Composition of Nucleic Acids
When a nucleic acid (DNA or RNA) is completely hydrolysed, it breaks down into three distinct types of simpler molecules:
Structure of Nucleic Acids
The first step in assembling a nucleic acid is attaching a base to the sugar. A base is linked to the position of the pentose sugar through a β-N-glycosidic linkage (the base's nitrogen bonds to the a…
Biological Functions of Nucleic Acids
DNA is the chemical basis of heredity — it can be thought of as the cell's permanent reserve of genetic information.
Hormones
Hormones are molecules that carry signals between cells, allowing one part of the body to instruct another.
+−Intext Questions 10.6-10.8i3 questions
- 10.6Why cannot vitamin C be stored in our body?Free
- 10.7What products would be formed when a nucleotide from DNA containing thymine is hydrolysed?Preview
- 10.8When RNA is hydrolysed, there is no relationship among the quantities of different bases obtained. What does this fact suggest about the str…Preview
Summary
- Carbohydrates: Polyhydroxy aldehydes or ketones. Classified as monosaccharides (e.g., glucose ), oligosaccharides (e.g., sucrose), and polysaccharides (e.g., starch, cellulose).
Exercises
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- 10.1What are monosaccharides?Free
- 10.2What are reducing sugars?Free
- 10.3Write two main functions of carbohydrates in plants.Free
- 10.4Classify the following into monosaccharides and disaccharides. Ribose, 2-deoxyribose, maltose, galactose, fructose and lactose.Preview
- 10.5What do you understand by the term glycosidic linkage?Preview
- 10.6What is glycogen? How is it different from starch?Preview
- 10.7What are the hydrolysis products of (i) sucrose and (ii) lactose?Preview
- 10.8What is the basic structural difference between starch and cellulose?Preview
- 10.9What happens when D-glucose is treated with the following reagents? (i) $HI$ (ii) Bromine water (iii) $HNO_3$Preview
- 10.10Enumerate the reactions of D-glucose which cannot be explained by its open chain structure.Preview
- 10.11What are essential and non-essential amino acids? Give two examples of each type.Preview
- 10.12Define the following as related to proteins: (i) Peptide linkage (ii) Primary structure (iii) DenaturationPreview
- 10.13What are the common types of secondary structure of proteins?Preview
- 10.14What type of bonding helps in stabilising the $\alpha$-helix structure of proteins?Preview
- 10.15Differentiate between globular and fibrous proteins.Preview
- 10.16How do you explain the amphoteric behaviour of amino acids?Preview
- 10.17What are enzymes?Preview
- 10.18What is the effect of denaturation on the structure of proteins?Preview
- 10.19How are vitamins classified? Name the vitamin responsible for the coagulation of blood.Preview
- 10.20Why are vitamin A and vitamin C essential to us? Give their important sources.Preview
- 10.21What are nucleic acids? Mention their two important functions.Preview
- 10.22What is the difference between a nucleoside and a nucleotide?Preview
- 10.23The two strands in DNA are not identical but are complementary. Explain.Preview
- 10.24Write the important structural and functional differences between DNA and RNA.Preview
- 10.25What are the different types of RNA found in the cell?Preview
Answers to Intext Questions
These are the final answers printed at the end of the NCERT chapter. The book gives answers for some intext questions only — every question below links to our complete worked solution.
NCERT Exemplar
Higher-order thinking problems from the NCERT Exemplar.
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- Q1Glycogen is a branched chain polymer of $\alpha$-D-glucose units in which chain is formed by C1-C4 glycosidic linkage whereas branching occu…Free
- Q2Which of the following polymers is stored in the liver of animals? (i) Amylose (ii) Cellulose (iii) Amylopectin (iv) GlycogenFree
- Q3Sucrose (cane sugar) is a disaccharide. One molecule of sucrose on hydrolysis gives _______. (i) 2 molecules of glucose (ii) 2 molecules of…Free
- Q4Anomers are two cyclic forms of the same monosaccharide that differ in configuration only at the anomeric carbon (the carbon that was the ca…Preview
- Q5Proteins are found to have two different types of secondary structures viz. $\alpha$-helix and $\beta$-pleated sheet structure. $\alpha$-hel…Preview
- Q6In a disaccharide, if the reducing groups (the aldehydic or ketonic/anomeric carbons) of BOTH monosaccharide units are used up in the glycos…Preview
- Q7Which of the following acids is a vitamin? (i) Aspartic acid (ii) Ascorbic acid (iii) Adipic acid (iv) Saccharic acidPreview
- Q8Dinucleotide is obtained by joining two nucleotides together by phosphodiester linkage. Between which carbon atoms of pentose sugars of nucl…Preview
- Q9Nucleic acids are the polymers of _______. (i) nucleosides (ii) nucleotides (iii) bases (iv) sugarsPreview
- Q10Which of the following statements is not true about glucose? (i) It is an aldohexose. (ii) On heating with HI it forms n-hexane. (iii) It is…Preview
- Q11Each polypeptide in a protein has amino acids linked with each other in a specific sequence. This sequence of amino acids is said to be ____…Preview
- Q12DNA and RNA contain four bases each. Which of the following bases is not present in RNA? (i) Adenine (ii) Uracil (iii) Thymine (iv) CytosinePreview
- Q13Which of the following B group vitamins can be stored in our body? (i) Vitamin B$_1$ (ii) Vitamin B$_2$ (iii) Vitamin B$_6$ (iv) Vitamin B$_…Preview
- Q14Which of the following bases is not present in DNA? (i) Adenine (ii) Thymine (iii) Cytosine (iv) UracilPreview
- Q15Three cyclic monosaccharide structures (labelled I, II and III) are drawn as Fischer projections closed by a ring oxygen, each ending in a C…Preview
- Q16Which of the following reactions of glucose can be explained only by its cyclic structure? (i) Glucose forms pentaacetate. (ii) Glucose reac…Preview
- Q17The prefixes D and L denote the configuration of the highest-numbered chiral carbon of a sugar (the chiral carbon nearest the terminal CH2OH…Preview
- Q18The disaccharide sucrose is formed from a glucose unit and a fructose unit. In the given structure the six carbons of the glucose ring are l…Preview
- Q19Three structures, labelled (A), (B) and (C), each show two glucose units joined by a glycosidic oxygen. In structure (A) the two six-membere…Preview
- Q20Name the sugar present in milk. How many monosaccharide units are present in it? What are such oligosaccharides called?Preview
- Q21How do you explain the presence of all the six carbon atoms in glucose in a straight chain?Preview
- Q22In nucleoside, a base is attached at the 1' position of the sugar moiety. Nucleotide is formed by linking of phosphoric acid unit to the sug…Preview
- Q23Name the linkage connecting monosaccharide units in polysaccharides.Preview
- Q24Under what conditions glucose is converted to gluconic and saccharic acid?Preview
- Q25Monosaccharides contain carbonyl group hence are classified as aldose or ketose. The number of carbon atoms present in the monosaccharide mo…Preview
- Q26The prefixes 'D' and 'L' before a sugar's name give the configuration of its reference carbon - the highest-numbered chiral carbon, i.e. the…Preview
- Q27Aldopentoses named ribose and 2-deoxyribose are found in nucleic acids. What is their relative configuration?Preview
- Q28Which sugar is called invert sugar? Why is it called so?Preview
- Q29Amino acids can be classified as $\alpha$-, $\beta$-, $\gamma$-, $\delta$- and so on depending upon the relative position of the amino group…Preview
- Q30$\alpha$-Helix is a secondary structure of proteins formed by twisting of polypeptide chain into right handed screw like structures. Which t…Preview
- Q31Some enzymes are named after the reaction, where they are used. What name is given to the class of enzymes which catalyse the oxidation of o…Preview
- Q32During curdling of milk, what happens to sugar present in it?Preview
- Q33How do you explain the presence of five —OH groups in glucose molecule?Preview
- Q34Consider compound (A): a cyclic (pyranose) form of glucose, drawn as a Fischer-type projection closed into a ring by an oxygen that joins th…Preview
- Q35Why must vitamin C be supplied regularly in diet?Preview
- Q36Sucrose is dextrorotatory but the mixture obtained after hydrolysis is laevorotatory. Explain.Preview
- Q37Amino acids behave like salts rather than simple amines or carboxylic acids. Explain.Preview
- Q38Structures of glycine and alanine are given below. Show the peptide linkage in glycylalanine.Preview
- Q39Protein found in a biological system with a unique three dimensional structure and biological activity is called a native protein. When a pr…Preview
- Q40The activation energy for the acid catalysed hydrolysis of sucrose is 6.22 kJ mol$^{-1}$, while the activation energy is only 2.15 kJ mol$^{…Preview
- Q41How do you explain the presence of an aldehydic group in a glucose molecule?Preview
- Q42Which moieties of nucleosides are involved in the formation of phosphodiester linkages present in dinucleotides? What does the word diester…Preview
- Q43What are glycosidic linkages? In which type of biomolecules are they present?Preview
- Q44Which monosaccharide units are present in starch, cellulose and glycogen and which linkages link these units?Preview
- Q45How do enzymes help a substrate to be attacked by the reagent effectively?Preview
- Q46Describe the term D- and L-configuration used for amino acids with examples.Preview
- Q47How will you distinguish 1° and 2° hydroxyl groups present in glucose? Explain with reactions.Preview
- Q48Coagulation of egg white on boiling is an example of denaturation of protein. Explain it in terms of structural changes.Preview
- Q49Write the reactions of D-glucose which cannot be explained by its open chain structure. How can cyclic structure of glucose explain these re…Preview
- Q50On the basis of which evidences D-glucose was assigned the following structure (the open chain structure of D-glucose)?Preview
- Q51Carbohydrates are essential for life in both plants and animals. Name the carbohydrates that are used as storage molecules in plants and ani…Preview
- Q52Explain the terms primary and secondary structure of proteins. What is the difference between $\alpha$-helix and $\beta$-pleated sheet struc…Preview
- Q53Write the structures of fragments produced on complete hydrolysis of DNA. How are they linked in DNA molecule? Draw a diagram to show pairin…Preview
- Q54Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a _______.…Preview
- Q55Proteins can be classified into two types on the basis of their molecular shape i.e., fibrous proteins and globular proteins. Examples of gl…Preview
- Q56Which of the following carbohydrates are branched polymer of glucose? (Note: one or more of the following options may be correct.) (i) Amylo…Preview
- Q57Amino acids are classified as acidic, basic or neutral according to the relative number of amino (-NH2) and carboxyl (-COOH) groups they con…Preview
- Q58Lysine, $\text{H}_2\text{N}(\text{CH}_2)_4\text{CH}(\text{NH}_2)\text{COOH}$, is _______. (Note: one or more of the following options may be…Preview
- Q59Which of the following monosaccharides are present as five membered cyclic structure (furanose structure)? (Note: one or more of the followi…Preview
- Q60In fibrous proteins, polypeptide chains are held together by _______. (Note: one or more of the following options may be correct.) (i) van d…Preview
- Q61Which of the following are purine bases? (Note: one or more of the following options may be correct.) (i) Guanine (ii) Adenine (iii) Thymine…Preview
- Q62Which of the following terms are correct about enzymes? (Note: one or more of the following options may be correct.) (i) Proteins (ii) Dinuc…Preview
- Q63Match the vitamins given in Column I with the deficiency disease they cause given in Column II. Column I (Vitamins): (A) Vitamin A; (B) Vita…Preview
- Q64Match the following enzymes given in Column I with the reactions they catalyse given in Column II. Column I (Enzymes): (A) Invertase; (B) Ma…Preview
- Q65Assertion (A): D(+)-Glucose is dextrorotatory in nature. Reason (R): 'D' represents its dextrorotatory nature. (i) Both A and R are true and…Preview
- Q66Assertion (A): Vitamin D can be stored in our body. Reason (R): Vitamin D is a fat soluble vitamin. (i) Both A and R are true and R is the c…Preview
- Q67Assertion (A): $\beta$-glycosidic linkage is present in maltose. Reason (R): Maltose is composed of two glucose units in which C-1 of one gl…Preview
- Q68Assertion (A): All naturally occurring $\alpha$-amino acids except glycine are optically active. Reason (R): Most naturally occurring amino…Preview
- Q69Assertion (A): Deoxyribose, $\text{C}_5\text{H}_{10}\text{O}_4$ is not a carbohydrate. Reason (R): Carbohydrates are hydrates of carbon so c…Preview
- Q70Assertion (A): Glycine must be taken through diet. Reason (R): It is an essential amino acid. (i) Both A and R are true and R is the correct…Preview
- Q71Assertion (A): In presence of enzyme, substrate molecule can be attacked by the reagent effectively. Reason (R): Active sites of enzymes hol…Preview
CBSE Sample Papers
Questions from official CBSE sample papers.
+−Show 6 questionsHide questions6 questions
- Q1What happens when D-glucose is treated with the following reagents? (1+1=2) (a) HI (b) Conc. $HNO_3$Preview
- Q2(A) Define the following term : (a) Reducing sugar (b) Differentiate between the following : (i) Fibrous proteins and globular proteins (ii)…Preview
- Q3On hydrolysis, which of the following carbohydrates gives only glucose? (A) Starch (B) Fructose (C) Lactose (D) SucrosePreview
- Q4Give the plausible explanation for the following: (a) Glucose doesn't give 2,4-DNP test. (b) The two strands in DNA are not identical but ar…Preview
- Q5Define the following terms: (i) Oligosaccharides (ii) Invert sugarPreview
- Q6Explain the following : (i) Amino acids behave like salts rather than simple amines or carboxylic acids. (ii) The two strands of DNA are com…Preview