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NCERT Exemplar · Q27

Q.The mother germ cells are transformed into a mature follicle through series of steps. Provide the missing steps in the blank boxes.

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Oogenesis is the process of forming a mature female gamete (ovum) from oogonia in the ovaries, involving mitotic proliferation, meiotic arrest, and follicular development.

Oogenesis is the intricate process by which the mother germ cells, known as oogonia, develop into a mature female gamete, or ovum. Unlike spermatogenesis, which is continuous, oogenesis is a discontinuous process that begins during fetal development and is completed only after puberty, upon fertilization. This journey involves not only the maturation of the oocyte itself but also the development of surrounding follicular cells, culminating in the formation of a mature follicle ready for ovulation.

The initial stages of oogenesis occur within the fetal ovary. During embryonic development, millions of oogonia are formed within each fetal ovary. These mother germ cells multiply by mitotic divisions, increasing their numbers. However, no more oogonia are formed or added after birth. As these oogonia grow, they enter the prophase-I stage of meiotic division and get arrested at this stage. At this point, they are called primary oocytes.

Note

The arrest of primary oocytes in prophase-I is a crucial difference from spermatogenesis, where meiosis begins only at puberty. This ensures a reserve of potential ova is established early in life.

Each primary oocyte then becomes surrounded by a single layer of granulosa cells. This structure is termed a primary follicle. A large number of these primary follicles degenerate during the period from birth to puberty. Consequently, at puberty, only about 60,000 to 80,000 primary follicles are left in each ovary.

With the onset of puberty, the development of these follicles resumes. The primary follicles become surrounded by more layers of granulosa cells and a new layer called the theca. This structure is now called a secondary follicle.

The secondary follicle then transforms into a tertiary follicle. A distinguishing feature of the tertiary follicle is the presence of a fluid-filled cavity called the antrum. At this stage, the primary oocyte within the tertiary follicle grows significantly in size and completes its first meiotic division. This division is unequal, resulting in the formation of a large haploid secondary oocyte and a tiny first polar body. The secondary oocyte retains the bulk of the nutrient-rich cytoplasm, which is essential for early embryonic development. The first polar body may or may not divide further.

Important

The completion of meiosis I and the formation of the secondary oocyte and first polar body occur before ovulation, within the tertiary follicle. The secondary oocyte immediately proceeds to metaphase II of meiosis and gets arrested there. …

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