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Q.a) Antibiotics are classified into broad spectrum antibiotics and narrow spectrum antibiotics. Write one example each for these antibiotics.

(1)
b) Write one similarity and one difference between antiseptics and disinfectants. (2)
Kerala DhseKerala DHSE Plus Two Board 2014Subjective· 3mImportance★★★★★
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Chloramphenicol illustrates a broad-spectrum antibiotic, penicillin G a narrow-spectrum one; antiseptics and disinfectants share a germicidal action but differ in where they can safely be applied.

a) Broad-spectrum vs narrow-spectrum antibiotics

Broad-spectrum antibiotics are effective against a wide range of both gram-positive and gram-negative bacteria (and sometimes other microorganisms). Example: Chloramphenicol (also ampicillin, tetracycline are valid examples).

Narrow-spectrum antibiotics are effective against only a limited/specific group of microorganisms, typically only gram-positive or only gram-negative bacteria. Example: Penicillin G (effective mainly against gram-positive bacteria).

b) Antiseptics vs disinfectants

Similarity: Both antiseptics and disinfectants are chemical substances that kill microorganisms or inhibit/prevent their growth (they are both germicidal/antimicrobial agents), and in fact the same chemical compound can sometimes act as either, depending on its concentration (e.g. a 0.2% solution of phenol acts as an antiseptic, while a 1% solution acts as a disinfectant).

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