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Q.Diagrammatic representation of 'Central dogma' is given below: Observe the diagram carefully and redraw it making appropriate corrections.

Kerala DhseKerala DHSE Plus Two Board 2014Subjective· 1mImportance★★★★★
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Figure — The (corrected) central-dogma flow diagram
Figure — The (corrected) central-dogma flow diagram

The printed diagram wrongly labels DNA→mRNA as 'translation' and mRNA→Protein as 'transcription'; the correct labels are the reverse.

The Central Dogma of molecular biology, first stated by Francis Crick, describes the normal one-way flow of genetic information in a cell:

DNA (replicates itself, shown by the looping arrow) → transcription → mRNA → translation → Protein

  • Transcription is the process of copying genetic information from one strand of DNA into a complementary sequence of mRNA — this must be the DNA-to-mRNA step.
  • Translation is the process of decoding the mRNA's codon sequence into a corresponding sequence of amino acids to build a polypeptide/protein — this must be the mRNA-to-Protein step. …

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