Q.Mother and father of a person with 'O' blood group have 'A' and 'B' blood group, respectively. What would be the genotype of both mother and father?
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Start your 14-day free trial to unlock the full solution →A child with O blood group must inherit one recessive i allele from each parent, so both parents must carry that allele — meaning the mother with A blood group is heterozygous (IAi) and the father with B blood group is heterozygous (IBi).
To understand this, we need to revisit the basics of ABO blood group inheritance as taught in NCERT. The ABO system is controlled by a single gene on chromosome 9, which has three alleles: IA, IB, and i. Both IA and IB are dominant over i, but they are codominant with each other — meaning if a person inherits both IA and IB, they express both and have AB blood group.
The possible genotypes and corresponding blood groups are:
- IAIA or IAi → A blood group
- IBIB or IBi → B blood group
- IAIB → AB blood group
- ii → O blood group
Now, the child in this question has O blood group. That means the child’s genotype must be ii — two recessive i alleles, one inherited from each parent. This is the crucial point: since the child has no dominant allele from either parent, each parent must have contributed an i allele.
The mother has A blood group. She could be either IAIA (homozygous) or IAi (heterozygous). But because she passed an i allele to her child, she cannot be IAIA — that genotype has no i allele to give. So the mother must be IAi, i.e., heterozygous for A.
Similarly, the father has B blood group. He could be IBIB or IBi. Since he also passed an i allele to the child, he cannot be IBIB. So the father must be IBi, i.e., heterozygous for B.
This is a classic example of how a recessive trait (O blood group) can appear in a child even when both parents show dominant phenotypes (A and B). The key is that both parents are carriers of the recessive i allele.
Now let’s look at the options given: …
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