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Question 102 of 117

Q.(a) A time-bound vaccination programme is followed for the children in our country from their birth up to ten years of age. A graph plotted below shows the effect of the vaccination followed by infection by the same pathogen, and the antibody concentration in the blood of the child.

(i) Explain why the administration of a vaccine causes an increase in the antibody concentration.
(ii) If the child is infected with the same pathogen almost four months later, the antibody concentration in his/her blood increases very fast. Explain why.
(iii) A table given below gives information about different types of immunity and how they are attained. Identify 'P', 'Q', 'R', 'S' and 'T' in the table. Type of immunity Production of antibodies Presence of memory cells Mode attained
(1) Natural, active Yes 'P' 'Q'
(2) Natural, passive No 'R' Across the placenta during pregnancy/breast feeding
(3) Acquired, active 'S' Yes Getting a vaccine during breast feeding
(4) Acquired, passive 'T' No Getting an injection of antibodies
(OR)
(b)
(i) What is the chemical name of 'smack' ? Why is the consumption of smack considered as an abuse ?
(ii) Name the source plant and one effect of the following drugs on the human body :
(1) Marijuana
(2) Cocaine
(3) Morphine
Lakshadweep CbseCBSE Class XII Board 2023Subjective· 5mImportance★★★★★
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Part (a): A vaccine causes a primary immune response (antibody production by plasma cells); a later infection triggers a rapid secondary response because of memory cells - P = Yes, Q = Getting the infection, R = No, S = Yes, T = No. Part (b): 'Smack' is heroin (diacetylmorphine) from Papaver somniferum, abused because it is an addictive depressant; Marijuana (Cannabis sativa), Cocaine (Erythroxylum coca) and Morphine (Papaver somniferum) each have characteristic effects.

Part (a)

  1. Why a vaccine raises antibody concentration. A vaccine contains antigens - weakened/inactivated pathogens or their antigenic parts. The immune system treats them as foreign: B-lymphocytes are activated and differentiate into plasma cells, which secrete large amounts of specific antibodies. This is the primary immune response and is seen as the first rise in antibody level.
  2. Why re-infection gives a very fast rise. During the primary response the body also makes long-lived memory B and T cells. When the same pathogen infects the child months later, these memory cells recognise it immediately and rapidly proliferate into plasma cells. The result is a secondary immune response that is quicker, stronger and reaches a higher antibody level than the first.
  3. Identifying the table.
Type of immunityAntibodiesMemory cellsMode attained
Natural, activeYesP = YesQ = By getting the infection (natural exposure)
Natural, passiveNoR = NoAcross placenta / breast feeding
Acquired, activeS = YesYesGetting a vaccine

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