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Q.The constant ratio for DNA is

(a) A+G/T+C
(b) A+T/G+C
(c) A+C/U+G
(d) A+U/C+G
Manipur CohsemCOHSEM Manipur Higher Secondary Board 2017MCQ· 1mImportance★★★★★
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Chargaff's equivalence rule shows that purines and pyrimidines occur in a fixed 1:1 ratio in double-stranded DNA because of complementary base pairing.

According to Chargaff's rule, in any double-stranded DNA molecule the amount of adenine (A) equals the amount of thymine (T), and the amount of guanine (G) equals the amount of cytosine (C), because A pairs specifically with T (via 2 hydrogen bonds) and G pairs specifically with C (via 3 hydrogen bonds) in the double helix. Consequently, the ratio of total purines (A+G) to total pyrimidines (T+C) is constant, and always equal to 1, regardless of the species or …

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