Preparation of Amines

Preparation of Amines

Amines are rarely built by attaching nitrogen directly; instead they are almost always obtained by transforming a nitrogen-containing functional group that is already present in some other compound. NCERT lays out six such routes, each starting from a different precursor and each with its own reach and its own limitation:

1. Reduction of nitro compounds — nitroalkanes/nitroarenes reduced catalytically or with metal–acid combinations.
2. Ammonolysis of alkyl halides — direct nucleophilic displacement of halide by ammonia. …