Q.Among the five factors that are known to affect Hardy-Weinberg equilibrium, three factors are gene flow, genetic drift and genetic recombination. What are the other two factors?
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Start your 14-day free trial to unlock the full solution →The other two factors that affect Hardy-Weinberg equilibrium are mutation and natural selection.
The Hardy-Weinberg principle describes an idealized population in genetic equilibrium where allele frequencies remain constant across generations. This equilibrium holds only when five specific conditions are met, and any deviation from these conditions will cause evolutionary change. You've already identified three of the five factors—gene flow, genetic drift, and genetic recombination—so let's understand what completes the picture.
The first of the remaining two factors is mutation. Mutations are the ultimate source of all genetic variation, introducing entirely new alleles into a population's gene pool. Even though individual mutations occur at very low rates, they represent the raw material upon which all other evolutionary forces act. A population experiencing recurrent mutation will see its allele frequencies shift over time, violating the Hardy-Weinberg equilibrium. Without mutation, there would be no new genetic variants to fuel evolutionary change.
The second factor is natural selection. This is perhaps the most powerful force disrupting Hardy-Weinberg equilibrium. When individuals with certain genotypes survive and reproduce at different rates because of environmental pressures, allele frequencies change directionally across generations. Natural selection can be directional (favoring one extreme phenotype), stabilizing (favoring intermediate forms), or disruptive (favoring both extremes). Unlike the random effects of genetic drift, selection is a non-random process that adapts populations to their environments. …
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