Q.The stability of chromosome is determined by ________.

Chromosomes are the compact, coiled structures that carry a cell's hereditary information, but they are only visible in this condensed form while the nucleus is dividing; for the rest of the cell cycle the same material exists as dispersed, granular-looking chromatin threads. Four features characterise every chromosome: its shape is specific and constant, interrupted by a short constricted centromere that always sits at the same position on a given chromosome; the number of chromosomes is fixed for each species (40 in the mouse, 16 in onion, 46 in humans); chromosomes occur in homologous pairs, one member inherited from each parent; and chromosomes are copied between nuclear divisions, producing two identical sister chromatids joined at a shared centromere. The centromere carries the kinetochore, a trilaminar DNA-protein complex that is the physical attachment site for spindle mic …