Q.Who discovered Prions?
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Start your 14-day free trial to unlock the full solution →Prions, infectious protein-only particles with no nucleic acid, were discovered by Stanley B. Prusiner.
When classifying life forms, biologists encounter a few entities that blur the line between living and non-living. Viruses have nucleic acid wrapped in protein; viroids (discovered by T.O. Diener) are even simpler — free RNA with no protein coat. Prions go a step further: they are purely proteinaceous infectious particles with NO nucleic acid at all. A prion is a misfolded version of a normal cellular protein; on contact, it converts the normal protein into the same misfolded, disease-causing form, allowing the abnormality to 'spread' without any genetic material being involved. This unusual mechanism causes neurodegenerative diseases such as scrapie in sheep, mad cow disease (BSE), and Creutzfeldt-Jakob disease in humans. Stanley B. Prusiner proposed and established this protein-only in …
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