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More Questions · Q13

Q.Lactose intolerance occurs because the body produces an insufficient amount of:

(a) Insulin
(b) Lactase
(c) Pepsin
(d) Amylase
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Lactose (milk sugar) must be split into glucose + galactose before it can be absorbed.

The enzyme that does this is lactase, made in the lining of the small intestine.

Too little lactase leaves lactose undigested → it ferments in the colon → gas, bloating, cramps, diarrhoea.

Correct option: (b) Lactase.

Concept understanding: why an enzyme is needed at all

Only monosaccharides — single sugar units such as glucose, fructose and galactose — can cross the wall of the small intestine into the blood. Lactose is a disaccharide: one glucose joined to one galactose. It is therefore far too large to be absorbed intact and must be cut in two first.

The scissors for that particular cut are the enzyme lactase, produced by the cells lining the small intestine (the brush border). Enzymes are specific — each one acts on one type of substrate — so no other digestive enzyme can substitute for lactase.

What goes wrong in lactose intolerance

  1. Lactase production falls (this is common after childhood and is especially frequent across Asia).
  2. The lactose in the milk drink is not split, so it is not absorbed.
  3. It passes on into the large intestine, where gut bacteria ferment it.
  4. Fermentation produces gases (hydrogen, carbon dioxide, methane) and draws water into the bowel.
  5. Result: bloating, wind, abdominal cramps and diarrhoea, typically 30 minutes to a couple of hours after the milk.
Important

Lactose intolerance is an enzyme deficiency, not a milk allergy. An allergy is an immune reaction to milk protein; intolerance is a digestive failure to break down milk sugar. The management is completely different.

Why the other options are wrong

OptionWhat it actually isWhy it cannot be the answer
(a) InsulinA hormone from the pancreasMoves glucose from blood into cells; its deficiency causes diabetes mellitus, not digestive symptoms after milk
(c) PepsinA stomach protein-digesting enzymeActs on proteins, not on sugars — no effect on lactose
(d) AmylaseA starch-digesting enzyme (saliva + pancreas)Breaks starch down to maltose; it has no action on lactose

Practical relevance for a sportsperson

Milk is a cheap, complete-protein recovery food in India, so an intolerant athlete needs alternatives that still deliver the protein and calcium: …

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