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Biology · Class 12 Science

Ch 7Human Health and Disease — Class 12 Biology, concept-first.

For a long time, health was understood through the idea of bodily 'humors' being in balance — a view held by early Greek physicians like Hippocrates and by the Indian Ayurvedic tradition alike.

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Key concepts

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Chapter contents

The NCERT structure, section by section. Open a section to see its questions, then read the concept-first solution.

Introduction

For a long time, health was understood through the idea of bodily 'humors' being in balance — a view held by early Greek physicians like Hippocrates and by the Indian Ayurvedic tradition alike.

7.1

Common Diseases in Humans

This section introduces the most common infectious diseases that affect humans — their causative agents, modes of transmission, symptoms, and basic preventive measures.

7.2

Immunity

The body’s ability to fight disease-causing organisms is called immunity. This is not a single mechanism but a coordinated system of cells, tissues, and chemical signals that recognise and neutralise…

7.2.1

Innate Immunity

Innate immunity is the body's first line of defence — it is present from birth and works against any foreign agent, regardless of what it is.

7.2.2

Acquired Immunity

Acquired immunity is fundamentally different from innate immunity. While innate immunity is a general, non-specific defence that works against any invader, acquired immunity is pathogen specific — it…

7.2.3

Active and Passive Immunity

The body’s immune system can be divided into two broad types based on how immunity is acquired: active immunity and passive immunity.

7.2.4

Vaccination and Immunisation

The immune system has a remarkable property: it remembers. Once your body fights off a pathogen, it keeps a stock of memory B-cells and T-cells that recognise that same invader instantly if it ever re…

7.2.5

Allergies

When you walk into a new place and start sneezing or wheezing for no obvious reason, only to have the symptoms vanish when you leave — that is a classic allergic reaction.

7.2.6

Auto Immunity

The immune system of higher vertebrates — including humans — has a remarkable ability: it can tell the difference between the body's own cells (self) and foreign invaders (non-self), such as bacteria,…

7.2.7

Immune System in the Body

The immune system is not a single organ but a distributed network. It includes lymphoid organs, tissues, cells, and soluble molecules like antibodies.

7.3

AIDS

AIDS stands for Acquired Immuno Deficiency Syndrome. The name itself tells you what it is: a deficiency of the immune system that is acquired during a person's lifetime — it is not a congenital (inher…

7.4

Cancer

Cancer is not a single disease but a broad term for a collection of related diseases. In all types of cancer, some of the body’s cells begin to divide without stopping and spread into surrounding tiss…

7.5

Drugs and Alcohol Abuse

Health is not just the absence of disease — it is a state of complete physical, mental and social well-being. Drug and alcohol abuse directly attacks all three dimensions.

7.5.1

Adolescence and Drug/Alcohol Abuse

Adolescence is not just a stretch of years — it is a transition. The word itself means both a period and a process, during which a child matures in attitudes and beliefs, learning to participate effec…

7.5.2

Addiction and Dependence

The core idea here is that drugs and alcohol are not just harmful in the moment — they trap the user through two distinct but linked mechanisms: addiction and dependence.

7.5.3

Effects of Drug/Alcohol Abuse

Drug and alcohol abuse does not only harm the person consuming them — the effects ripple outward, damaging relationships, families, and society.

7.5.4

Prevention and Control

The central idea in preventing drug and alcohol abuse is the old saying: prevention is better than cure.

Summary

- Health and its dimensions: Health is a state of complete physical, mental and social well-being, not merely the absence of disease.

Exercises

+Show 17 questions17 questions
  1. 7.1What are the various public health measures, which you would suggest as safeguard against infectious diseases?Free
  2. 7.2In which way has the study of biology helped us to control infectious diseases?Free
  3. 7.3How does the transmission of each of the following diseases take place? (a) Amoebiasis (b) Malaria (c) Ascariasis (d) PneumoniaFree
  4. 7.4What measure would you take to prevent water-borne diseases?Preview
  5. 7.5Discuss with your teacher what does 'a suitable gene' means, in the context of DNA vaccines.Preview
  6. 7.6Name the primary and secondary lymphoid organs.Preview
  7. 7.7The following are some well-known abbreviations, which have been used in this chapter. Expand each one to its full form: (a) MALT (b) CMI (c…Preview
  8. 7.8Differentiate the following and give examples of each: (a) Innate and acquired immunity (b) Active and passive immunityPreview
  9. 7.9Draw a well-labelled diagram of an antibody molecule.Preview
  10. 7.10What are the various routes by which transmission of human immuno-deficiency virus takes place?Preview
  11. 7.11What is the mechanism by which the AIDS virus causes deficiency of immune system of the infected person?Preview
  12. 7.12How is a cancerous cell different from a normal cell?Preview
  13. 7.13Explain what is meant by metastasis.Preview
  14. 7.14List the harmful effects caused by alcohol/drug abuse.Preview
  15. 7.15Do you think that friends can influence one to take alcohol/drugs? If yes, how may one protect himself/herself from such an influence?Preview
  16. 7.16Why is that once a person starts taking alcohol or drugs, it is difficult to get rid of this habit? Discuss it with your teacher.Preview
  17. 7.17In your view what motivates youngsters to take to alcohol or drugs and how can this be avoided?Preview

NCERT Exemplar

Higher-order thinking problems from the NCERT Exemplar.

+Show 70 questions70 questions
  1. Q1The term 'Health' is defined in many ways. The most accurate definition of the health would be: (a) Health is the state of body and mind in…Free
  2. Q2The organisms which cause diseases in plants and animals are called: (a) Pathogens (b) Vectors (c) Insects (d) WormsFree
  3. Q3The clinical test that is used for diagnosis of typhoid is: (a) ELISA (b) ESR (c) PCR (d) WidalFree
  4. Q4Diseases are broadly grouped into infectious and non-infectious diseases. In the list given below, identify the infectious diseases. i. Canc…Preview
  5. Q5The sporozoites that cause infection when a female Anopheles mosquito bites a person, are formed in: (a) liver of the person (b) RBCs of mos…Preview
  6. Q6The disease chikunguniya is transmitted by: (a) house fly (b) Aedes mosquito (c) cockroach (d) female AnophelesPreview
  7. Q7Many diseases can be diagnosed by observing the symptoms in the patient. Which group of symptoms are indicative of pneumonia? (a) Difficulty…Preview
  8. Q8Cancer causing genes are called: (a) structural genes (b) expressor genes (c) oncogenes (d) regulatory genesPreview
  9. Q9In malignant tumors, the cells proliferate, grow rapidly and move to other parts of the body to form new tumors. This stage of disease is ca…Preview
  10. Q10When an apparently healthy person is diagnosed as unhealthy by a psychiatrist, the reason could be that: (a) the patient was not efficient a…Preview
  11. Q11Which of the following are the reason(s) for Rheumatoid arthritis? Choose the correct option. i. The ability to differentiate pathogens or f…Preview
  12. Q12AIDS is caused by HIV. Among the following, which one is not a mode of transmission of HIV? (a) Transfusion of contaminated blood (b) Sharin…Preview
  13. Q13'Smack' is a drug obtained from the: (a) latex of Papaver somniferum (b) leaves of Cannabis sativa (c) flowers of Dhatura (d) fruits of Eryt…Preview
  14. Q14The substance produced by a cell in viral infection that can protect other cells from further infection is: (a) serotonin (b) colostrum (c)…Preview
  15. Q15Transplantation of tissues/organs to save certain patients often fails due to rejection of such tissues/organs by the patient. Which type of…Preview
  16. Q16Antibodies present in colostrum which protect the new born from certain diseases is of (a) Ig G type (b) Ig A type (c) Ig D type (d) Ig E ty…Preview
  17. Q17Tobacco consumption is known to stimulate secretion of adrenaline and nor-adrenaline. The component causing this could be: (a) Nicotine (b)…Preview
  18. Q18Antivenom against snake poison contains: (a) Antigens (b) Antigen-antibody complexes (c) Antibodies (d) EnzymesPreview
  19. Q19Which of the following is not a lymphoid tissue? (a) Spleen (b) Tonsils (c) Pancreas (d) ThymusPreview
  20. Q20Which of the following glands is large sized at birth but reduces in size with ageing? (a) Pineal (b) Pituitary (c) Thymus (d) ThyroidPreview
  21. Q21Haemozoin is a: (a) precursor of hemoglobin (b) toxin released from Streptococcus infected cells (c) toxin released from Plasmodium infected…Preview
  22. Q22Which of the following is not the causal organism for ringworm? (a) Microsporum (b) Trichophyton (c) Epidermophyton (d) MacrosporumPreview
  23. Q23A person with sickle cell anemia is (a) more prone to malaria (b) more prone to typhoid (c) less prone to malaria (d) less prone to typhoidPreview
  24. Q24Certain pathogens are tissue/organ specific. Justify the statement with suitable examples.Preview
  25. Q25The immune system of a person is suppressed. In the ELISA test, he was found positive to a pathogen. a. Name the disease the patient is suff…Preview
  26. Q26Where are B-cells and T-cells formed? How do they differ from each other?Preview
  27. Q27Given below are the pairs of pathogens and the diseases caused by them. Which out of these is not a matching pair and why? (a) Virus — commo…Preview
  28. Q28What would happen to immune system, if thymus gland is removed from the body of a person?Preview
  29. Q29Many microbial pathogens enter the gut of humans along with food. What are the preventive barriers to protect the body from such pathogens?…Preview
  30. Q30Why is mother's milk considered the most appropriate food for a new born infant?Preview
  31. Q31What are interferons? How do interferons check infection of new cells?Preview
  32. Q32An antibody molecule is drawn as a Y-shaped structure built from four polypeptide chains held together by inter-chain disulfide (–S–S–) brid…Preview
  33. Q33If a regular dose of drug or alcohol is not provided to an addicted person, he shows some withdrawal symptoms. List any four such withdrawal…Preview
  34. Q34Why is it that during changing weather, one is advised to avoid closed, crowded and airconditioned places like cinema halls etc.?Preview
  35. Q35The harmful allele of sickle cell anemia has not been eliminated from human population. Such afflicted people derive some other benefit. Dis…Preview
  36. Q36Lymph nodes are secondary lymphoid organs. Explain the role of lymph nodes in our immune response.Preview
  37. Q37Why is an antibody molecule represented as H2L2?Preview
  38. Q38What does the term 'memory' of the Immune system mean?Preview
  39. Q39If a patient is advised Anti Retroviral Therapy, which infection is he suffering from? Name the causative organism.Preview
  40. Q40Differentiate between active immunity and passive immunity.Preview
  41. Q41Differentiate between benign tumor and malignant tumor.Preview
  42. Q42Do you consider passive smoking is more dangerous than active smoking? Why?Preview
  43. Q43"Prevention is better than cure". Comment.Preview
  44. Q44Explain any three preventive measures to control microbial infections.Preview
  45. Q45In the given flow diagram, the replication of retrovirus in a host is shown. Observe and answer the following questions. a. Fill in (1) and…Preview
  46. Q46"Maintenance of personal and public hygiene is necessary for prevention and control of many infectious diseases". Justify the statement givi…Preview
  47. Q47The following table shows certain diseases, their causative organisms and symptoms. Fill the gaps. (i) Disease: Ascariasis; Causative organi…Preview
  48. Q48The outline structure of a drug is given below. a. Which group of drugs does this represent? b. What are the modes of consumption of these d…Preview
  49. Q49Give the full form of CT and MRI. How are they different from each other? Where are they used?Preview
  50. Q50Many secondary metabolites of plants have medicinal properties. It is their misuse that creates problems. Justify the statement with an exam…Preview
  51. Q51Why cannabinoids are banned in sports and games?Preview
  52. Q52What is secondary metabolism?Preview
  53. Q53Drugs and alcohol give short-term 'high' and long-term 'damages', Discuss.Preview
  54. Q54Diseases like dysentery, cholera, typhoid etc., are more common in over crowded human settlements. Why?Preview
  55. Q55From which plant cannabiniods are obtained? Name any two cannabinoids. Which part of the body is effected by consuming these substances?Preview
  56. Q56In the metropolitan cities of India, many children are suffering from allergy/asthma. What are the main causes of this problem. Give some sy…Preview
  57. Q57What is the basic principle of vaccination? How do vaccines prevent microbial infections? Name the organism from which hepatitis B Vaccine i…Preview
  58. Q58What is cancer? How is a cancer cell different from the normal cell? How do normal cells attain cancerous nature?Preview
  59. Q59A person shows strong unusual hypersensitive reactions when exposed to certain substances present in the air. Identify the condition. Name t…Preview
  60. Q60For an organ transplant, it is an advantage to have an identical twin. Why?Preview
  61. Q61What are lifestyle diseases? How are they caused? Name any two such diseases.Preview
  62. Q62If there are two pathogenic viruses, one with DNA and other with RNA, which would mutate faster? And Why?Preview
  63. Q63Represent schematically the life cycle of a malarial parasite.Preview
  64. Q64Compare the life style of people living in the urban areas with those of rural areas and briefly describe how the life style affects their h…Preview
  65. Q65Why do some adolescents start taking drugs. How can this be avoided?Preview
  66. Q66In your locality, if a person is addicted to alcohol, what kind of behavioural changes do you observe in that person? Suggest measures to ov…Preview
  67. Q67What are the methods of cancer detection? Describe the common approaches for treatment of cancer.Preview
  68. Q68Drugs like LSD, barbiturates, amphetamines, etc., are used as medicines to help patients with mental illness. However, excessive doses and a…Preview
  69. Q69What is Pulse Polio Programme of Government of India? What is OPV? Why is it that India is yet to eradicate Polio?Preview
  70. Q70What are recombinant DNA vaccines? Give two examples of such vaccines. Discuss their advantages.Preview

CBSE Sample Papers

Questions from official CBSE sample papers.

+Show 30 questions30 questions
  1. Q1Name any two physiological barriers that provide innate immunity. OR Select two disease resistant crop varieties from the list of crop varie…Preview
  2. Q2Explain the relationship between B-lymphocytes and T-lymphocytes in developing an immune response.Preview
  3. Q3While on an excursion to a hill station, some of the children developed allergic symptoms. (a) List any two allergic symptoms. (b) Name any…Preview
  4. Q4State the functions of mast cells in allergy response. OR State the function of interpherons.Preview
  5. Q5The main barrier that prevents the entry of micro-organisms into our body is (A) Antibodies (B) Macrophages (C) Monocytes (D) SkinPreview
  6. Q6It is often observed that the chances of a person suffering from measles in his or her lifetime are low if he or she has suffered from the d…Preview
  7. Q7A student on a field trip suddenly felt breathlessness and started to sneeze very badly. Name this response and explain what it is due to.Preview
  8. Q8Name the type of immunity the mother provides the newborn baby. How does it happen ?Preview
  9. Q9The principle of vaccination is based on the property of (A) Specificity (B) Diversity (C) Memory (D) Discrimination between ‘self’ and ‘non…Preview
  10. Q10Mention the chemical nature of an antibody and name the type of cells they are produced by. Write the difference between active and passive…Preview
  11. Q11When Plasmodium sp. (malarial parasite) enters the human body, it reproduces asexually and increases its number. During this course, the aff…Preview
  12. Q12(a) Name and state the type of immunity that acts as a ‘biological shield’ to the developing foetus against many infections in the mother’s…Preview
  13. Q13Explain, giving two reasons, how immune response by “vaccine” is different from that by “antitoxin” in humans.Preview
  14. Q14Ringworm is one of the most common infectious fungal disease in humans. Name any two genera of fungi which cause ringworm and state any of i…Preview
  15. Q15(a) A time-bound vaccination programme is followed for the children in our country from their birth up to ten years of age. A graph plotted…Preview
  16. Q16Assertion (A) : More and more children in metro cities of India suffer from allergies and asthma due to sensitivity to the environment. Reas…Preview
  17. Q17In which of the following conditions/diseases is there a substantial increase in the activity of mast cells observed in the human body? (A)…Preview
  18. Q18(a) A farmer while working on his farm was bitten by a poisonous snake. He was rushed to a nearby health centre where the doctor gave him an…Preview
  19. Q19Assertion (A) : Virus-infected cells produce interferons. Reason (R) : Interferons can cause inflammation of virus-infected cells. (A) Both…Preview
  20. Q20(a) Differentiate between humoral immune response and cell-mediated immune response. (b) Draw a schematic diagram of an antibody molecule an…Preview
  21. Q21(a) (i) Describe the life cycle of Plasmodium from the time it enters the human body till a female Anopheles mosquito bites an infected pers…Preview
  22. Q22Colostrum secreted by the mother's mammary glands in a human female during the initial days of lactation is rich in antibody : (A) IgE (B) I…Preview
  23. Q23(a) (i) Explain why the milk produced by the mother during the initial days of lactation is considered to be very essential for the newborn…Preview
  24. Q24(a) Define Humoral immune response. (b) Name any two types of antibodies found to give humoral immune response in humans.Preview
  25. Q25(a) (i) Name the protozoan species that is responsible for causing the most serious and even fatal malarial disease. (ii) Name the host in w…Preview
  26. Q26What is the role of histamine released by mast cells ? (A) Lowers blood pressure (B) Causes allergic symptoms (C) Stimulates antibody format…Preview
  27. Q27(a) A person inhales dust and pathogens but does not always fall sick. Explain how the body protects against such infections. (b) Name and d…Preview
  28. Q28Name two diseases whose spread can be controlled by the eradication of Aedes mosquitoes.Preview
  29. Q29How do cytokine barriers provide innate immunity in humans?Preview
  30. Q30(a) Name the source plant of heroin drug. How is it obtained from the plant? (b) Write the effects of heroin on the human body.Preview