Q.Deficient secretion of ADH (vasopressin), or the kidney's failure to respond to it, results in the passage of a large volume of dilute urine accompanied by excessive thirst — a condition called

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Deficient ADH secretion or response causes diabetes insipidus -- large volumes of dilute urine and exc …

ADH (antidiuretic hormone, vasopressin) normally increases the permeability of the DCT and collecting duct to water, allowing water to be reabsorbed and concentrated urine to be produced. When ADH secretion by the posterior pituitary is deficient, or when the kidney's collecting ducts fail to respond to circulating ADH, the tubule remains largely impermeable to water regardless of the body's hydration state, so a very large volume of dilute, watery urine is passed each day, and the resulting water loss drives intense, persistent …

Link the described symptoms (large dilute urine volume + thirst) directly to loss of ADH action on the collecting duct, and recall the specific name giv …

Confusing diabetes insipidus (a water-regulation disorder caused by ADH deficiency) with diabetes mellitus (a blood-glucose disorder caused by insulin deficiency/resistance) -- the …