Q.What do you think the doctors inject to induce delivery?
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🔒 Start your 14-day free trial to unlock the full solution →Concept understanding — Parturition Hormonal Control
Let’s begin with something you already know. When a baby is ready to be born, the mother’s body doesn’t just “decide” one day — it follows a precise, hormone-driven sequence. Think of it like a carefully timed relay race: one hormone passes the baton to the next, and each step triggers the next until labour begins.
The everyday intuition
Imagine you are waiting for a train. The station master doesn’t just blow the whistle randomly. First, the train arrives at the platform, then the guard checks the signal, then the whistle blows, and only then does the train move. Parturition — the process of giving birth — works the same way. The baby’s body sends the first signal, the mother’s body receives it, and a chain of hormonal commands follows. No signal, no movement.
What parturition means
Parturition is the medical term for childbirth — the expulsion of the fully developed baby from the mother’s uterus. In NCERT Class 12 Biology (Chapter: Human Reproduction), it is described as the process that begins with the onset of labour and ends with the delivery of the baby and the placenta.
The key point: parturition is not a sudden event. It is the climax of a hormonal cascade that starts weeks earlier.
The hormonal relay: step by step
The entire process is controlled by a feedback loop between the baby’s brain, the mother’s hypothalamus, and her uterus. Here is the sequence as NCERT presents it:
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The baby’s brain starts it. As the foetus grows, its hypothalamus matures and releases corticotropin-releasing hormone (CRH). This hormone travels to the foetal pituitary gland.
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Foetal pituitary secretes ACTH. ACTH (adrenocorticotropic hormone) stimulates the foetal adrenal glands to produce cortisol.
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Cortisol from the foetus acts on the placenta. The placenta, which connects mother and baby, responds by producing oestrogen in increasing amounts. At the same time, progesterone levels fall.
The shift from high progesterone to high oestrogen is the critical switch. Progesterone keeps the uterus relaxed (quiet). Oestrogen makes the uterine muscle sensitive to contraction signals. Without this shift, labour cannot begin.
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Oestrogen stimulates the uterus to produce oxytocin receptors. The mother’s posterior pituitary gland also releases oxytocin — the hormone that causes strong, rhythmic contractions of the uterine muscles.
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Oxytocin creates a positive feedback loop. Each contraction pushes the baby’s head against the cervix. This stretching of the cervix sends nerve signals back to the mother’s brain, which releases more oxytocin. More oxytocin → stronger contractions → more stretching → even more oxytocin. This cycle continues until the baby is delivered.
Why this matters
- It explains why labour cannot be induced artificially without medical intervention — the baby’s own hormones must first signal readiness.
- It also explains why stress or illness in the mother can delay labour: if the foetal cortisol signal is weak, the oestrogen shift may not happen on time.
- In some cases, doctors use synthetic oxytocin (Pitocin) to start or strengthen labour — this mimics the natural hormone.
A quick summary of the key hormones
| Hormone | Source | Role in parturition |
|---|---|---|
| CRH | Foetal hypothalamus | Starts the cascade |
| ACTH | Foetal pituitary | Stimulates foetal adrenal glands |
Oxytocin (typically as a synthetic form, e.g. Pitocin). This is directly grounded in the same paragraph's own explanation: oxytocin, released from the maternal pituitary, is the hormone that acts on the uterine muscle to cause stronger contractions during natural parturition — doctors inject a synthetic version of this same hormone to induce or augment labour when needed. …
Doctors induce delivery by injecting oxytocin (a synthetic form) — the same hormone the section has just described as the driver of natural uterine contractions during parturition.
Section 2.7 explains the foetal ejection reflex: signals from the fully developed foetus and placenta trigger mild uterine contractions, which trigger release of oxytocin from the maternal pituitary. Oxytocin acts on the uterine muscle to cause stronger contractions, which in turn stimulate further oxytocin release — a positive-feedback loop that builds until the baby is delivered. …
- AP EAPCET 2024Set ap-2024-05-17-FN1 markMCQQ.Assertion (A): Neurohypophysis of the pituitary gland releases a hormone, which is helpful for child birth Reason (R): Neurohypophysis releases relaxin, which contracts the uterine muscles during child birth (A) A and R are true. R is correct explanation for A (B) A and R are true. But R is not correct explanation for A (C) A is true. But R is false (D) A is false. But R is true
›Reveal solutionSolution
The assertion (neurohypophysis aids childbirth) is true because it releases oxytocin, but the reason is false because it wrongly names relaxin (a different hormone from a different gland) as the contracting agent.
Concept and Intuition
The neurohypophysis (posterior pituitary) stores and releases two hormones synthesized in the hypothalamus: oxytocin and vasopressin (ADH). Oxytocin is crucial during childbirth: it stimulates strong, coordinated contractions of the uterine smooth muscle (myometrium) during labour (parturition), and later stimulates milk ejection during lactation. Relaxin, in contrast, is a completely different hormone secreted by the corpus luteum of the ovary and by the placenta; its role is to relax (soften) the pelvic ligaments and dilate/soften the cervix in preparation for delivery — the opposite functional role (relaxation, not contraction) and from a different source gland.
Step-by-Step Solution
- Evaluate Assertion: Does the neurohypophysis release a hormone helpful for childbirth? Yes — oxytocin. True.
- Evaluate Reason: Does the neurohypophysis release relaxin, which contracts uterine muscles? No — relaxin is from the corpus luteum/placenta, and its function is to relax (not contract) tissues. False. …
- AP EAPCET 2021Set ap-2021-09-03-AN1 markMCQQ.Assertion (A): Myometrium is an important component of Uterus Reason (R): Myometrium produces strong contractions during parturition (A) Both A and R are correct and R is not correct explanation for A (B) Both A and R are correct and R is correct explanation for A (C) Both A and R are wrong (D) A is correct but R is wrong
›Reveal solutionSolution
This tests uterine histology: the myometrium's contractile smooth muscle is exactly why it is functionally important, especially during labour.
Concept and Intuition
The uterine wall has three layers: perimetrium (outer), myometrium (middle, smooth muscle), and endometrium (inner, glandular). The myometrium's job is contraction — it thickens during pregnancy and, near term, produces the powerful, coordinated contractions of labour (parturition) that push the baby through the birth canal. Its importance as a uterine component is precisely because of this contractile role.
Step-by-Step Solution
- Assertion: Myometrium is an important component of the uterus — TRUE, as it forms the bulk of the uterine wall and drives all uterine movements.
- Reason: Myometrium produces strong contractions during parturition — TRUE, this is a well-established physiological fact (oxytocin-triggered labour contractions). …
- AP EAPCET 2021Set ap-2021-09-06-AN1 markMCQQ.Assertion (A): Generally, a woman does not conceive during the lactation period Reason (R): The hormone 'Prolactin' initiates and maintains lactation in a delivered woman (A) Both A and R are correct and R is the correct explanation of A (B) Both A and R are correct and R is not the correct explanation of A (C) A is correct but R is wrong (D) A is wrong but R is correct
›Reveal solutionSolution
Both the assertion (no conception during lactation) and the reason (prolactin initiates/maintains lactation) are individually true facts, but the reason given does not causally explain the assertion — the real mechanism is prolactin's suppression of ovulation-triggering hormones, not merely its role in milk production.
Concept and Intuition
During lactation, elevated prolactin levels (which are essential for initiating and sustaining milk secretion from the mammary glands) also happen to inhibit the pulsatile release of GnRH from the hypothalamus, which in turn suppresses FSH and LH secretion from the pituitary. Since ovulation depends on properly timed FSH/LH surges, this suppression prevents ovulation, and hence conception, during intense lactation — a phenomenon known as lactational amenorrhea. So the assertion is a real physiological phenomenon, and the reason describes a true, related fact about prolactin, but it doesn't state the actual causal link (suppression of gonadotropins/ovulation); it only describes prolactin's role in milk production.
Step-by-Step Solution
- Assertion: women generally do not conceive during lactation — true (lactational amenorrhea is a recognized, if not absolutely reliable, natural contraceptive effect).
- Reason: prolactin initiates and maintains lactation — true, this is prolactin's defining physiological role. …
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