Q.Write an example for auto immune disease.
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An autoimmune disorder occurs when the immune system's ability to distinguish the body's own tissue ("self") from foreign material ("non-self") breaks down, causing it to mount a sustained attack on the body's own healthy cells. Rheumatoid arthritis is a well-known example that specifically affects the joints, causing chronic inflammation, pain, swelling, and progressive joint damage; other autoimmune conditions target different tissues, such as the thyroid gland or skin. Because the underlying misdirect …
In autoimmune disorders the immune system mistakenly attacks the body's own tissues, so a valid example is a condition in which self-tissue (here, …
Rheumatoid arthritis is a standard example of an autoimmune disease.
In autoimmune disorders the body's immune system attacks its own cells and tissues. In rheumatoid arthritis, the immune system attacks the tissues o …
- CBSE 2026Set ANNUAL1 markMCQQ.Rheumatoid arthritis is which type of disease?(a) Sex-linked disease(b) Genetic disease(c) Viral disease(d) Autoimmune disease
›Reveal solutionSolution
Rheumatoid arthritis is a chronic autoimmune condition in which the immune system attacks the tissues lining the joints, causing inflammation and pain.
An autoimmune disease occurs when the body's immune system fails to distinguish 'self' from 'non-self' and mounts an immune response against its own cells or tissues. In rheumatoid arthritis, immune cells and antibodies attack the synovial membrane lining the joints, leading to chronic inflammation, pain, swelling and eventual joint damage.
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- CBSE 2025Set 57/4/11 markMCQQ.In which of the following human diseases does the body's self-defence mechanism attack self-cells ? (A) Thalassemia (B) Phenylketonuria (C) Filariasis (D) Rheumatoid arthritis
›Reveal solutionSolution
Rheumatoid arthritis is an autoimmune disease where the body's immune system mistakenly attacks its own healthy joint tissues, making it the correct answer.
Our immune system is a sophisticated defence mechanism designed to protect us from foreign invaders like bacteria, viruses, and parasites. It achieves this by distinguishing between "self" cells (our own body cells) and "non-self" cells (foreign entities). This ability to differentiate is crucial for maintaining health. However, sometimes this mechanism goes awry, leading to conditions where the immune system loses its tolerance for self-cells and begins to attack them. These conditions are known as autoimmune diseases.
Let's examine each option to determine which one fits this description.
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Thalassemia: This is a genetic blood disorder. It's caused by mutations in the DNA that affect the production of hemoglobin, the protein in red blood cells that carries oxygen. The body's immune system does not attack its own cells in thalassemia; rather, there's a defect in the red blood cell production itself.
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Phenylketonuria (PKU): This is also a genetic metabolic disorder. Individuals with PKU lack a specific enzyme (phenylalanine hydroxylase) needed to break down the amino acid phenylalanine. This leads to a buildup of phenylalanine in the body, which can cause neurological problems. Like thalassemia, PKU is not an autoimmune disease; it's a problem with metabolism due to a genetic defect.
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Filariasis: This is an infectious disease caused by parasitic worms called filariae. These worms are transmitted to humans through mosquito bites. The immune system responds to the presence of these parasites, but it is attacking a foreign invader, not the body's own cells. Therefore, it is not an autoimmune disease. …
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- CBSE 2023Set A1 markQ.Write name of any one autoimmune disease.
›Reveal solutionSolution
An autoimmune disease occurs when the immune system fails to distinguish self from non-self and attacks the body's own tissues; rheumatoid arthritis is one example.
Normally the immune system distinguishes the body's own (self) cells from foreign (non-self) antigens. In autoimmune disorders, this recognition fails, and the immune system attacks the body's own cells/tissues, causing damage. Rheumatoid arthritis is a common example, in which the immune system attacks the joints, causing inflammation, pain, and p …
- CBSE 2022Set M1 markQ.Write an example for auto immune disease.
›Reveal solutionSolution
Rheumatoid arthritis is a standard example of an autoimmune disease.
In autoimmune disorders the body's immune system attacks its own cells and tissues. In rheumatoid arthritis, the immune system attacks the tissues o …
- CBSE 2017Set ANNUAL1 markQ.What is an Auto-immune disorders?
›Reveal solutionSolution
In auto-immunity, the immune system loses its ability to distinguish self from non-self and attacks the body's own tissues.
Normally the immune system distinguishes the body's own ('self') molecules from foreign ('non-self') ones and attacks only the latter. In auto-immune disorders, this self-tolerance breaks down, and the immune system produces antibodies or activated immune cells against the body's own healthy cells and tissues, causing damage/disease. Examples include rheumatoid art …
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