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Exercises · 2.11

Q.Give a brief account of viruses with respect to their structure and nature of genetic material. Also name four common viral diseases.

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Viruses are non-cellular, obligate parasites made of a nucleic acid core (RNA or DNA, never both) wrapped in a protein coat; common viral diseases include mumps, small pox, herpes and influenza.

Structure and nature of viruses

  • Viruses are non-cellular organisms characterised by an inert crystalline structure outside the living cell. W.M. Stanley (1935) showed they could be crystallised.
  • Once they infect a cell, they take over its machinery to replicate themselves, killing the host; hence they are obligate parasites.
  • A virus is a nucleoprotein — its protein coat, called the capsid, is made of small subunits called capsomeres, which protect the nucleic acid.
  • These capsomeres are arranged in helical or polyhedral geometric forms (e.g., the helical Tobacco Mosaic Virus and the polyhedral-headed bacteriophage).

Nature of genetic material

  • In addition to proteins, a virus contains genetic material that is either RNA or DNA — no virus contains both RNA and DNA.
  • In general: plant-infecting viruses have single-stranded RNA; animal-infecting viruses have single- or double-stranded RNA or double-stranded DNA; and bacteriophages (bacterial viruses) are usually double-stranded DNA viruses.
  • The genetic material is infectious. …

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