Q.In a Mendelian monohybrid cross, the F2 generation shows identical genotypic and phenotypic ratios. What does it tell us about the nature of alleles involved? Justify your answer.
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Start your 14-day free trial to unlock the full solution →When the F2 generation of a monohybrid cross shows identical genotypic and phenotypic ratios, it indicates that the alleles involved exhibit either incomplete dominance or co-dominance, meaning the heterozygous genotype produces a distinct phenotype.
Mendelian genetics, as established by Gregor Mendel, forms the bedrock of our understanding of heredity. A monohybrid cross involves studying the inheritance of a single trait by crossing two true-breeding parents that differ in that trait. For instance, crossing a true-breeding tall pea plant with a true-breeding dwarf pea plant. The first filial (F1) generation consists of hybrids, and when these F1 individuals are self-pollinated, they produce the second filial (F2) generation.
Under the principle of complete dominance, which Mendel primarily observed and described, one allele completely masks the expression of the other in the heterozygous state. In a monohybrid cross exhibiting complete dominance, the F1 generation would uniformly express the dominant trait. When these F1 individuals are self-pollinated, the F2 generation typically shows:
- A phenotypic ratio of 3:1 (three individuals expressing the dominant trait for every one expressing the recessive trait).
- A genotypic ratio of 1:2:1 (one homozygous dominant, two heterozygous, and one homozygous recessive).
Notice that in complete dominance, these ratios are not identical. The reason for this difference is that the heterozygous genotype (e.g., Tt for tallness) expresses the same phenotype (tall) as the homozygous dominant genotype (TT). This means two different genotypes (TT and Tt) result in the same observable trait, leading to the 3:1 phenotypic ratio despite the 1:2:1 genotypic distribution.
However, the question describes a scenario where the F2 generation shows identical genotypic and phenotypic ratios. This is a crucial deviation from typical Mendelian complete dominance and tells us something fundamental about how the alleles interact.
For the genotypic and phenotypic ratios to be identical in the F2 generation of a monohybrid cross, each distinct genotype must correspond to a distinct phenotype.
This condition is met when the alleles involved exhibit either incomplete dominance or co-dominance.
- Incomplete Dominance: In this case, neither allele is completely dominant over the other. The heterozygous individual expresses an intermediate phenotype that is distinct from both homozygous parents. A classic example is the snapdragon flower colour, where a cross between a true-breeding red flower (RR) and a true-breeding white flower (rr) produces F1 offspring that are all pink (Rr). When these pink F1 plants are self-pollinated, the F2 generation will show:
- 1 Red (RR) : 2 Pink (Rr) : 1 White (rr) as the genotypic ratio.
- 1 Red : 2 Pink : 1 White as the phenotypic ratio. Here, the genotypic ratio (1:2:1) is identical to the phenotypic ratio (1:2:1) because the heterozygous genotype (Rr) produces a unique, intermediate phenotype (pink) that is distinguishable from both homozygous phenotypes (red and white). …
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