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NCERT Exemplar · Q32

Q.Old people have weak immune system. What could be the reason?

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Weak immunity in old age results from the age-related degeneration of the thymus gland, which lowers thymosin output and, with it, immune-cell development.

The thymus gland, positioned in the chest between the two lungs, secretes a group of peptide hormones called thymosins. These hormones are central to keeping the immune system supplied: they drive the differentiation of T-lymphocytes, the white blood cells responsible for cell-mediated immunity, and they also promote the production of antibodies, which gives humoral immunity. …

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