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Question 44 of 46

Q.(a) What are the functions of Liver? OR

(b) Explain in detail the steps involved in Respiration.
Tamil Nadu DgeTamil Nadu HSC First Year (DGE) Board 2025Subjective· 5mImportance★★★★★
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The liver is the body's largest gland and central metabolic organ, performing digestive (bile secretion), metabolic, detoxifying, storage, and blood-related functions.

Answering part (a): What are the functions of Liver?

  1. Secretion of bile: liver (hepatic) cells continuously produce bile, containing bile salts and bile pigments (like bilirubin, from breakdown of haemoglobin). Bile is stored/concentrated in the gallbladder and released into the duodenum, where its bile salts emulsify large fat globules into smaller droplets, aiding fat digestion and absorption, and also help absorb fat-soluble vitamins (A, D, E, K).

  2. Carbohydrate metabolism: the liver stores excess glucose as glycogen (glycogenesis) after a meal, and breaks glycogen back down into glucose (glycogenolysis) when blood sugar falls, helping maintain stable blood glucose levels; it can also make new glucose from non-carbohydrate sources (gluconeogenesis).

  3. Protein metabolism: the liver synthesises important plasma proteins (such as albumin and clotting factors like fibrinogen and prothrombin), and carries out deamination of excess amino acids.

  4. Detoxification and excretion: the liver converts the highly toxic ammonia produced by deamination into the much less toxic urea (via the ornithine/urea cycle) for safe excretion by the kidneys; it also detoxifies drugs, alcohol, and other harmful substances absorbed from the gut.

  5. Fat metabolism: the liver is involved in the synthesis and breakdown of fats and cholesterol, and in the formation of lipoproteins that transport fats in blood.

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