Uremia

Uremia is the clinical name for a build-up of urea and other non-protein nitrogenous wastes - including uric acid and creatinine - in the blood, and it is a direct consequence of the kidneys losing their ability to clear these substances efficiently. A normal blood urea level is roughly 17-30 mg per 100 mL of blood; during chronic renal failure this can rise to as much as ten times that normal level, and the resulting toxicity is w …