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Evaluation · Q60

Q.Explain ribosomal translocation in protein synthesis.

Tamil Nadu DgeTextbookSubjectiveImportance★★★★★
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Step 1. During elongation, an incoming aminoacyl-tRNA pairs with the mRNA codon in the A-site while the growing chain sits in the P-site.

Step 2. A peptide bond forms between the P-site and A-site amino acids, catalysed by the ribosome's peptidyl-transferase activity, transferring the chain onto the A-site tRNA.

Step 3. The ribosome then moves exactly one codon further along the mRNA -- translocation, requiring GTP hydrolysis. …

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