Q.Addison's disease, marked by chronic fatigue, low blood pressure and darkened skin, results from hypofunction of the

[!TLDR]

Addison's disease results from hypofunction of the adrenal cortex, reducing cortisol and …

Addison's disease is caused by destruction or hypofunction of the adrenal cortex -- not the adrenal medulla -- leading to deficient secretion of both glucocorticoids (cortisol) and mineralocorticoids (aldosterone). The resulting symptoms -- chronic weakness, low blood pressure, salt craving and patchy darkening of the sk …

Recall that Addison's disease specifically affects the STEROID-hormone-secreting cortex of the adrenal gland, not the catecholamine-secreting medulla -- the symptoms (low BP, salt craving, …

Confusing Addison's disease (adrenal cortex hypofunction) with a disorder of the adrenal medulla -- the medulla's hormones (adrenalin …