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MCQ · Q6

Q.Which of the following disorders is an autoimmune disease in which antibodies are directed against the acetylcholine receptors of the neuromuscular junction, producing progressive muscle fatigue and weakness?

(a) Muscular dystrophy
(b) Tetany
(c) Myasthenia gravis
(d) Osteoporosis
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Myasthenia gravis is an autoimmune disease in which the body produces antibodies against its own acetylcholine receptors at the neuromuscular junction, so that acetylcholine released by the motor neuron can no longer effectively trigger a new action potential in the muscle fibre. This progressively impairs nerve-to-muscle signal transmission, causing muscle fatigue and weakness that worsens with repeated use, and can progress to paralysis in severe cases. Muscular dystrophy is instead …

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