Exercises · 16.7
Q.Bile juice contains no digestive enzymes, yet it is important for digestion. Why?
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Start your 14-day free trial to unlock the full solution →Bile, secreted continuously by the liver and stored/concentrated in the gall bladder before release into the duodenum, indeed contains no digestive enzymes. It is made up mainly of bile pigments (bilirubin and biliverdin, breakdown products of haemoglobin), bile salts, cholesterol, and phospholipids. Despite lacking enzymes, bile is indispensable to digestion for several reasons:
- Emulsification of fats: Bile salts act as detergents, breaking large, insoluble fat globules in the food into much smaller droplets dispersed in the watery intestinal contents. This emulsification enormously increases the total surface area of fat exposed to the fat-digesting lipase enzymes (pancreatic and intestinal lipase), which can then hydrolyse it far more effectively than they could a few large globules.
- Neutralising stomach acid: Bile is alkaline, and it helps neutralise the acidic chyme arriving from the stomach, bringing the duodenal contents to a pH at which pancreatic enzymes (which need a near-neutral to slightly alkaline environment) can function optimally.
- Aiding absorption: Bile salts also help package the products of fat digestion (fatty acids, monoglycerides) along with fat-soluble vitamins (A, D, E, K) into tiny micelles, which can then be absorbed by the intestinal mucosal cells. …
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