Biology · Ch 12 — Biotechnology
Healthcare Biotechnology
Healthcare Biotechnology
Healthcare biotechnology refers to medicinal or diagnostic products, or vaccines, developed using biotechnology, and it has had a tremendous impact on meeting patient needs. It offers patients unique, targeted and personalised therapeutic and diagnostic solutions -- for organ transplantation, stem-cell technology, genetic counselling, forensic medicine, gene probes, genetic fingerprinting and karyotyping are all outcomes of this branch of biotechnology. Table 12.7 lists a range of human recombinant proteins now produced by rDNA technology specifically to treat disease -- for example, erythropoietin for anaemia, insulin for diabetes, Factor VIII and Factor IX for haemophilia A and B, tissue plasminogen activator for blood clots, interferons for cancer, and the hepatitis B va …
| Disease/Condition | Recombinant Protein/Product |
|---|---|
| Anaemia | Erythropoietin |
| Asthma | Interleukin-1 receptor |
| Atherosclerosis | Platelet-derived growth factor |
| Parturition (childbirth) | Relaxin |
| Blood clots | Tissue Plasminogen Activator (TPA), Urokinase |
| Cancer | Interferons, tumour necrosis factor, interleukins, macrophage-activating factor |
| Diabetes | Insulin |
| Emphysema | Alpha-1 antitrypsin |