Exercises · 16.11
Q.Why are cimetidine and ranitidine better antacids than sodium hydrogencarbonate or magnesium or aluminium hydroxide ?
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Start your 14-day free trial to unlock the full solution →There are two different ways to counter excess stomach acid:
- Simple neutralizing antacids (sodium hydrogencarbonate, magnesium hydroxide, aluminium hydroxide) act by chemically neutralizing acid that has already been secreted into the stomach. This gives quick but temporary relief, and can sometimes stimulate the stomach to produce even more acid afterward (acid rebound).
- Cimetidine and ranitidine work differently — they are H2-receptor antagonists (blockers). They bind to and block the histamine H2 receptors on the acid-secreting cells of the stomach lining, preventing histamine from stimulating acid secretion at its source, so much less acid is produced in the first place. …
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