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Exercises · 10.1

Q.What is the average cell cycle span for a mammalian cell?

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✓ Free question

A typical mammalian cell in culture divides roughly once every 24 hours, though this timing is not fixed and varies with organism and cell type.

The cell cycle is the ordered sequence of events by which a cell grows, copies its genome and finally splits into two daughter cells. A convenient way to measure how long this takes is to study human cells grown in culture, because they divide in a fairly regular manner.

Such cells complete one full cell cycle in about 24 hours on average. It is worth being clear about what this figure does and does not mean:

  • It is an average value, not a constant for all life. The length of the cycle differs from one organism to another, and even different cell types within the same organism can take different amounts of time.
  • Yeast cells, for instance, run through an entire cell cycle in only about 90 minutes, which is far quicker than a human cell.
Note

Within the 24-hour span of a human cell, the visibly dramatic division stage (the M phase) lasts only about one hour. The remaining time, more than 95 per cent of the cycle, is taken up by interphase, when the cell is quietly growing and duplicating its DNA in preparation for division.

✓Final answer

The average cell cycle span for a mammalian cell in culture is about 24 hours, of which the actual division takes only around an hour.

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