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Evaluation · Q35

Q.How is sex determined in human beings?

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Step 1. State the human chromosome set: of the 23 pairs, 22 are autosomes (44A) and one pair is the sex chromosomes — XX in a normal female, XY in a normal male.

Step 2. State each parent's gamete output: the homogametic mother produces only one type of egg, always carrying a single X chromosome (22A+X); the heterogametic father produces two types of sperm in roughly equal numbers, one carrying an X chromosome (22A+X) and one carrying a Y chromosome (22A+Y).

Step 3. Combine at fertilisation: an egg (always X) fertilised by an X-bearing sperm gives a 44A+XX zygote, developing as female; an egg fertilised by a Y-bearing sperm gives a 44A+XY zygote, developing as male. Because the egg's contribution is fixed, it is entirely the father's sperm type that decides the outcome. …

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