Chemistry · Class 12 Science
Ch 14Biomolecules — Class 12 Chemistry, concept-first.
Every living thing is built from biomolecules -- carbohydrates, proteins, lipids and nucleic acids -- assembled from just five major elements: carbon, hydrogen, oxygen, nitrogen and phosphorus.
Key concepts
Hover a concept to preview it and jump to its most relevant Q&A.
Configuration of Carbohydrates (D/L System)
Almost every carbohydrate is optically active because it has one or more chiral carbons, and the number of possible stereoisomers follows the 2ⁿ rule (n = number of chiral carbons).
Most relevant Q&A
- Which one of the following rotates the plane polarized light towards left? (NEET Phase – II) a) D(+) Glucose b) L(+) Glucose c) D(-) Fructos…Free
- Why carbohydrates are generally optically active.Preview
- Is the following sugar, D–sugar or L–sugar? Fischer projection: CHO at C1; C2 – OH on the right (H on left); C3 – OH on the right (H on left…Preview
- What are Epimers ? Give example.Preview
Chapter contents
The NCERT structure, section by section. Open a section to see its questions, then read the concept-first solution.
Introduction
Every living thing is built from biomolecules -- carbohydrates, proteins, lipids and nucleic acids -- assembled from just five major elements: carbon, hydrogen, oxygen, nitrogen and phosphorus.
Carbohydrates
Carbohydrates are the most abundant organic compounds found in every living organism. They are also called saccharides, a name that comes from the Greek word 'sakcharon' meaning sugar, because a large…
Configuration of Carbohydrates
A carbohydrate molecule is almost always optically active because it possesses one or more chiral (asymmetric) carbon atoms -- carbons attached to four different groups.
Classification of Carbohydrates
Carbohydrates are classified into three major groups based on their product of hydrolysis. Monosaccharides are the simple sugars that cannot be hydrolysed into any smaller carbohydrate unit; oligosacc…
Glucose
Glucose is a simple sugar that serves as the major energy source for the human body. It is the most important and most abundant monosaccharide, occurring free in honey and in sweet fruits such as grap…
Fructose
Fructose is another commonly encountered monosaccharide, sharing the same molecular formula as glucose (C₆H₁₂O₆) but differing in its properties: it is levorotatory and is a ketohexose rather than an…
Disaccharides
Disaccharides are sugars that yield two molecules of monosaccharides on hydrolysis, a reaction usually catalysed by dilute acid or by a specific enzyme.
Polysaccharides
Polysaccharides consist of large numbers of monosaccharide units bonded together by glycosidic bonds and are the most common form of carbohydrate found in nature.
Importance of Carbohydrates
Carbohydrates, being widely distributed throughout the plant and animal kingdoms, act mainly in two broad capacities: as energy sources and as structural polymers.
Proteins
Proteins are the most abundant biomolecules in all living organisms. The term protein is derived from the Greek word 'proteios', meaning primary or holding first place, a name that reflects their cent…
Amino Acids
Amino acids are compounds that contain both an amino group and a carboxylic acid group in the same molecule.
Classification of α-Amino Acids
Amino acids are classified primarily on the nature of their R group, commonly called the side chain. Based on the chemical character of this side chain, amino acids are grouped as acidic, basic or neu…
Properties of Amino Acids
Amino acids are colourless, water-soluble crystalline solids. Because each molecule carries both a carboxyl group and an amino group, their acid-base behaviour differs from that of ordinary amines or…
Peptide Bond Formation
The amino acids that make up a protein are joined together covalently by peptide bonds. A peptide bond forms when the carboxyl group of one amino acid reacts with the amino group of a second amino aci…
Classification of Proteins
Proteins are classified, based on their overall structure (shape), into two major types: fibrous proteins and globular proteins.
Structure of Proteins
Proteins are polymers of amino acids, and their three-dimensional structure depends mainly on the sequence of amino acids (the residues) making up the chain.
Denaturation of Proteins
Each protein has a unique three-dimensional structure held together by interactions such as disulphide bonds, hydrogen bonds, and hydrophobic and electrostatic interactions.
Importance of Proteins
Proteins are the functional units of living things and play a vital role in essentially all biological processes.
Enzymes
A great many biochemical reactions occur continuously inside living cells: the digestion of food and the harvesting of energy from it, and the synthesis of the many molecules required for various cell…
Mechanism of Enzyme Action
Enzymes are biocatalysts that catalyse one specific biochemical reaction. In general, an enzyme speeds up its reaction by reducing the activation energy of that reaction, achieved by stabilising the h…
Lipids
Lipids are organic molecules that are soluble in organic solvents such as chloroform and methanol, and insoluble in water. The word 'lipid' is derived from the Greek word 'lipos', meaning fat.
Classification of Lipids
Based on their structures, lipids are classified as simple lipids, compound lipids and derived lipids.
Biological Importance of Lipids
Lipids serve a wide range of biological roles. (1) Lipids are an integral component of the cell membrane and are necessary for the structural integrity of the cell.
Vitamins
Vitamins are small organic compounds that cannot be synthesised by our body but that are essential for certain body functions; because the body cannot make them itself, they must be obtained through t…
Classification of Vitamins
Vitamins are classified into two groups based on their solubility, either in water or in fat.
Nucleic Acids
The inherent characteristics of each and every species are transmitted from one generation to the next.
Composition and Structure of Nucleic Acids
Nucleic acids are biopolymers of nucleotides. Controlled hydrolysis of either DNA or RNA yields three types of component: a nitrogenous base, a pentose sugar and a phosphate group.
Double Strand Helix Structure of DNA
In the early 1950s, Rosalind Franklin and Maurice Wilkins used X-ray diffraction to unravel the structure of DNA.
Types of RNA Molecules
Ribonucleic acids are similar in overall composition to DNA, but cells contain up to eight times as much RNA as DNA.
Biological Functions of Nucleic Acids
In addition to their well-known role as the structural subunits of the nucleic acids, nucleotides carry out a variety of other, independent functions in every cell.
More to Know: DNA Fingerprinting
Traditionally, one of the most accurate methods for placing an individual at the scene of a crime has been a fingerprint.
Hormones
A hormone is an organic substance (for example a peptide or a steroid) that is secreted by one tissue, enters the bloodstream, and induces a physiological response (for example growth or a change in m…
EVALUATION
45 Q+−Choose the Best Answer25 questions
- Q1Which one of the following rotates the plane polarized light towards left? (NEET Phase – II) a) D(+) Glucose b) L(+) Glucose c) D(-) Fructos…Free
- Q2The correct corresponding order of names of four aldoses with configuration given below respectively is, (NEET Phase – I) a) L-Erythrose, L-…Free
- Q3Which one given below is a non-reducing sugar? (NEET Phase – I) a) Glucose b) Sucrose c) maltose d) LactoseFree
- Q4Glucose --(HCN)--> Product --(hydrolysis)--> Product --(HI + Heat)--> A, the compound A is a) Heptanoic acid b) 2-Iodohexane c) Heptane d) H…Preview
- Q5Assertion: A solution of sucrose in water is dextrorotatory. But on hydrolysis in the presence of little hydrochloric acid, it becomes levor…Preview
- Q6The central dogma of molecular genetics states that the genetic information flows from (NEET Phase – II) a) Amino acids → Protein → DNA b) D…Preview
- Q7In a protein, various amino acids linked together by (NEET Phase – I) a) Peptide bond b) Dative bond c) α-Glycosidic bond d) β-Glycosidic bo…Preview
- Q8Among the following the achiral amino acid is (AIIMS) a) 2-ethylalanine b) 2-methylglycine c) 2-hydroxymethylserine d) TryptophanPreview
- Q9The correct statement regarding RNA and DNA respectively is (NEET Phase – I) a) the sugar component in RNA is an arabinose and the sugar com…Preview
- Q10In aqueous solution of amino acids mostly exists in, a) NH₂-CH(R)-COOH b) NH₂-CH(R)-COO⁻ c) H₃N⁺-CH(R)-COOH d) H₃N⁺-CH(R)-COO⁻Preview
- Q11Which one of the following is not produced by body? a) DNA b) Enzymes c) Harmones d) VitaminsPreview
- Q12The number of sp² and sp³ hybridised carbon in fructose are respectively a) 1 and 4 b) 4 and 2 c) 5 and 1 d) 1 and 5Preview
- Q13Vitamin B2 is also known as a) Riboflavin b) Thiamine c) Nicotinamide d) PyridoxinePreview
- Q14The pyrimidine bases present in DNA are a) Cytosine and Adenine b) Cytosine and Guanine c) Cytosine and Thiamine d) Cytosine and UracilPreview
- Q15Among the following L-serine is a) H₂N-C(=NH)-NH-CH₂-CH₂-CH₂-CH(NH₂)-COOH (guanidino side chain) b) (imidazol-4-yl)-CH₂-CH(NH₂)-COOH (five-m…Preview
- Q16The secondary structure of a protein refers to a) fixed configuration of the polypeptide backbone b) hydrophobic interaction c) sequence of…Preview
- Q17Which of the following vitamins is water soluble? a) Vitamin E b) Vitamin K c) Vitamin A d) Vitamin BPreview
- Q18Complete hydrolysis of cellulose gives a) L-Glucose b) D-Fructose c) D-Ribose d) D-GlucosePreview
- Q19Which of the following statement is not correct? a) Ovalbumin is a simple food reserve in egg-white b) Blood proteins thrombin and fibrinoge…Preview
- Q20Glucose is an aldose. Which one of the following reactions is not expected with glucose? a) It does not form oxime b) It does not react with…Preview
- Q21If one strand of the DNA has the sequence ‘ATGCTTGA’, then the sequence of complementary strand would be a) TACGAACT b) TCCGAACT c) TACGTACT…Preview
- Q22Insulin, a hormone chemically is a) Fat b) Steroid c) Protein d) CarbohydratesPreview
- Q23α-D (+) Glucose and β-D (+) glucose are a) Epimers b) Anomers c) Enantiomers d) Conformational isomersPreview
- Q24Which of the following are epimers a) D(+)-Glucose and D(+)-Galactose b) D(+)-Glucose and D(+)-Mannose c) Neither (a) nor (b) d) Both (a) an…Preview
- Q25Which of the following amino acids are achiral? a) Alanine b) Leucine c) Proline d) GlycinePreview
+−Write Brief Answer20 questions
- Q1What type of linkages hold together monomers of DNA?Free
- Q2Give the differences between primary and secondary structure of proteins.Free
- Q3Name the Vitamins whose deficiency cause i) rickets ii) scurvyFree
- Q4Write the Zwitter ion structure of alaninePreview
- Q5Give any three difference between DNA and RNAPreview
- Q6Write a short note on peptide bondPreview
- Q7Give two difference between Hormones and vitaminsPreview
- Q8Write a note on denaturation of proteinsPreview
- Q9What are reducing and non–reducing sugars?Preview
- Q10Why carbohydrates are generally optically active.Preview
- Q11Classify the following into monosaccharides, oligosaccharides and polysaccharides. i) Starch ii) fructose iii) sucrose iv) lactose v) maltos…Preview
- Q12How are vitamins classifiedPreview
- Q13What are harmones? Give examplesPreview
- Q14Write the structure of all possible dipeptides which can be obtained from glycine and alaninePreview
- Q15Define enzymesPreview
- Q16Write the structure of α-D (+) glucopyranosePreview
- Q17What are different types of RNA which are found in cellPreview
- Q18Write a note on formation of α-helix.Preview
- Q19What are the functions of lipids in living organism.Preview
- Q20Is the following sugar, D–sugar or L–sugar? Fischer projection: CHO at C1; C2 – OH on the right (H on left); C3 – OH on the right (H on left…Preview
Sample & Board Papers
Sample papers and previous-year board questions for this subject.
+−Show 20 questionsHide questions20 questions
- Q1The building block of proteins are : (a) $\alpha$-hydroxy acid (b) $\alpha$-amino acid (c) $\beta$-hydroxy acid (d) $\beta$-amino acidPreview
- Q2Raffinose on hydrolysis gives : (a) two monosaccharides (b) three monosaccharides (c) one disaccharide and one monosaccharide (d) two monosa…Preview
- Q3Sucrose is not : (a) hydrolysed to only glucose (b) a disaccharide (c) hydrolysed to glucose and fructose (d) a non-reducing sugarPreview
- Q4The amino acid without chiral carbon is : (a) proline (b) glycine (c) thyrosine (d) alaninePreview
- Q5Sucrose contains glucose and fructose linked by : (a) $C_1-C_6$ (b) $C_1-C_4$ (c) $C_1-C_2$ (d) $C_1-C_1$Preview
- Q6What is the action of conc. HI with glucose ?Preview
- Q7What is glycerose ? How is it obtained ?Preview
- Q8Draw the structure of Fructose. Mention the number of Chiral Carbon atoms and number of optical isomers present in it.Preview
- Q9Which of the following amino acids are achiral ? (a) Proline (b) Alanine (c) Glycine (d) LeucinePreview
- Q10What are Epimers ? Give example.Preview
- Q11Which of the following base is **not** present in DNA ? (a) Uracil (b) Adenine (c) Cytosine (d) GuaninePreview
- Q12What are Hormones ? Give example.Preview
- Q13Give the structure of a Zwitter ion.Preview
- Q14The pyrimidine bases present in RNA are : (a) Cytosine and Thiamine (b) Cytosine and Adenine (c) Cytosine and Uracil (d) Cytosine and Guanin…Preview
- Q15Write the structure of the following : $\alpha$-D-glucopyranose and $\beta$-D-glucopyranosePreview
- Q16Write a short note on peptide bond.Preview
- Q17The secondary structure of a protein refers to ________. (a) sequence of $\alpha$-amino acids (b) fixed configuration of the polypeptide bac…Preview
- Q18Mention any three functions of lipids in living organism.Preview
- Q19$\alpha$-D(+) Glucose and $\beta$-D(+) Glucose are : (a) Enantiomers (b) Epimers (c) Conformational isomers (d) AnomersPreview
- Q20What are harmones ? Give examples.Preview