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Q.What type of linkages hold together monomers of DNA?
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✓ Free question
Step 1. DNA is a biopolymer whose repeating monomer unit is the nucleotide, itself built from a nitrogenous base, a deoxyribose sugar and a phosphate group (§14.5.1).
Step 2. Phosphoric acid forms a bond called a phosphodiester bond that bridges two neighbouring nucleotides: specifically, the phosphate group attached at the 5'-OH of one nucleotide's sugar forms an ester linkage to the free 3'-OH of the next nucleotide's sugar.
Step 3. Repeating this 5'→3' phosphodiester linkage many thousands of times over builds up the full polynucleotide chain, i.e. one strand of DNA.
✓Final answer
Phosphodiester bonds link the nucleotide monomers of DNA together.
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