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Question 42 of 70

Q.Dinitrophenol is :

(a) an antibody
(b) a chemical group reacts with immunogen
(c) an antigen
(d) not an immunogen but reacts with pre-formed antibodies
Tamil Nadu DgeTamil Nadu HSC (DGE) Board 2019MCQ· 1mImportance★★★★★
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Dinitrophenol is a hapten: too small to trigger an immune response alone, yet able to bind pre-formed antibodies raised against it when carrier-coupled.

A hapten is a low-molecular-weight chemical group that cannot by itself induce an immune response, because it cannot engage the multiple receptors needed to activate lymphocytes; however, once it is coupled to a large carrier protein and used to immunise, the antibodies produced can specifically recognise and bind the free hapten on its own. Dinitrophenol is the textbook example used to illustrate this hapten behaviour in immunology. It is not itself an antibody, and calling it simply 'a chemical group that reacts with immunogen …

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