Q.From their examination of the structure of DNA, what did Watson and Crick infer about the probable mechanism of DNA replication, coding capability and mutation?
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Concept understanding — DNA Replication
DNA replication is semiconservative: the two parental strands of the double helix separate, and each serves as a template for a new complementary strand, so every daughter duplex retains exactly one original parental strand. Taylor, Woods and Hughes proved this experimentally in Vicia faba root cells using 3H-thymidine labelling and autoradiography: after one replication round both sister chromatids of every chromosome were labelled, but after a second round only one of the two sister chromatids per chromosome remained labelled, exactly matching the semiconservative prediction. In eukaryotes, replication begins simultaneously at many chromosomal origins of replic …
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