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MCQ · Q1

Q.Which plasma protein is chiefly responsible for maintaining the osmotic pressure (colloidal osmotic pressure) of blood that keeps water from leaking out of capillaries into the tissues?

(a) Fibrinogen
(b) Albumin
(c) Globulin
(d) Prothrombin
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✓ Free question

Step 1. Colloidal osmotic pressure is the pressure that pulls water back into capillaries from the surrounding tissue fluid, keeping plasma volume from leaking away.

Step 2. Among the plasma proteins, albumin is both the smallest and the most numerous, and it is chiefly responsible for generating this osmotic pull.

Step 3. Fibrinogen's role is clotting, globulins mainly carry antibodies/hormones/fats, and prothrombin is a clotting-cascade precursor — none of these is the main osmotic-pressure protein.

✓Final answer

(b) Albumin

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