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Long Answer Questions · Q28

Q.Describe the composition of human blood in detail, covering the constituents of plasma and the structure, count and principal function of each type of formed element (RBC, the different WBCs, and platelets).

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Step 1 — Plasma. Roughly fifty-five percent of blood volume; ~90-92% water; carries the plasma proteins albumin (osmotic pressure), globulins (antibodies, transport) and fibrinogen (clotting precursor), plus dissolved nutrients (glucose, amino acids, lipids), hormones, nitrogenous wastes (urea) and gases (mainly CO2 as bicarbonate).

Step 2 — Red blood cells. ~5-5.5 million/mm3; biconcave, enucleate, haemoglobin-packed; produced in red bone marrow, live ~120 days, destroyed mainly in the spleen; function is O2 (and some CO2) transport.

Step 3 — White blood cells. ~6,000-8,000/mm3, nucleated; granulocytes (neutrophils — most abundant, phagocytic; eosinophils — anti-parasitic/allergic; basophils — histamine/heparin) and agranulocytes (lymphocytes — B/T cells, specific immunity; monocytes — phagocytic, become tissue macrophages); function is defence.

Step 4 — Platelets. ~1.5-3.5 lakh/mm3; anucleate fragments of megakaryocytes; lifespan ~5-9 days; function is triggering blood coagulation at an injury site.

✓Final answer

Plasma (water, albumin/globulin/fibrinogen, nutrients, hormones, wastes, gases) + RBC (biconcave, enucleate, haemoglobin, O2 transport) + WBC (granulocytes + agranulocytes, defence) + platelets (anucleate fragments, clotting).

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