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Long Answer Questions · Q27

Q.Describe, with reference to cell shape, arrangement and location, the structure and functions of simple epithelium (squamous, cuboidal, columnar and ciliated) and of compound (stratified) epithelium.

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Step 1 — Simple squamous epithelium. Made of a single layer of flat, plate-like cells with a central flattened nucleus, fitted together like tiles. Because the cells are extremely thin, this epithelium lines the alveoli of the lungs and the walls of blood capillaries, where its function is to permit rapid diffusion of respiratory gases and small molecules across a minimal barrier.

Step 2 — Simple cuboidal epithelium. Made of a single layer of cube-shaped cells with a central, rounded nucleus. It lines the tubules of the kidney and the ducts of many glands, where its somewhat greater cell volume compared to squamous cells supports its function of active secretion and absorption.

Step 3 — Simple columnar epithelium. Made of a single layer of tall, pillar-shaped cells, often interspersed with mucus-secreting goblet cells. It lines the stomach and intestine, where its function is secretion (of mucus and digestive substances) and absorption of digested nutrients.

Step 4 — Ciliated epithelium. A modification of columnar or cuboidal epithelium in which the free surface bears motile, hair-like cilia. It lines the trachea, bronchioles and fallopian tubes, where the coordinated beating of the cilia functions to sweep mucus, trapped particles, or the ovum along the length of the tube.

Step 5 — Compound (stratified) epithelium. Made of several layers of cells stacked on top of one another, with new cells produced at the base pushing older, flattening cells towards the surface. The epidermis of the skin is the standard example, being stratified squamous epithelium, whose function is protection of the underlying tissue against mechanical wear, abrasion and, in the skin, water loss and pathogen entry — a role no single-layered epithelium could withstand.

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Simple epithelia (squamous/cuboidal/columnar/ciliated) are each a single cell layer specialised for diffusion, secretion/absorption, or surface clearance; compound (stratified) epithelium, as in the skin epidermis, is many layers thick and specialised for protection against wear.

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