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Evidence for Evolution · Q8

Q.Describe molecular evidence for evolution. How do similarities in DNA base sequences and in the amino-acid sequence of proteins such as cytochrome-c across different species help biologists work out how closely related those species are?

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Step 1. Cytochrome-c is a respiration protein present, in some closely similar form, in almost every aerobically respiring organism, making it useful for comparison across a huge range of species.

Step 2. Comparing the amino-acid sequence of cytochrome-c (or DNA base sequence) between two species counts how many differences separate them.

Step 3. Recently diverged species show few sequence differences; anciently diverged species show many more, since mutations accumulate independently within each lineage after it splits off.

Step 4. This sequence-difference count acts as a rough molecular 'clock' for how long ago two lineages diverged. …

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