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MCQ · Q2

Q.The hormone principally responsible for triggering ovulation through a sudden mid-cycle surge is

(a) FSH
(b) Oestrogen
(c) LH
(d) Progesterone
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As the Graafian follicle matures late in the follicular phase, its rising oestrogen output briefly switches the pituitary's usual negative feedback into positive feedback, producing a sharp mid-cycle surge of LH (with a smaller accompanying rise in FSH). This LH surge is the direct trigger that causes the mature follicle to rupture and release the secondary oocyte -- ovulation. FSH drives earlier follicular growth, oestrogen drives endometrial proliferation, and progesterone dominates only after ovulation, in the luteal phase.

[!ANSWER]

(c) LH

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