Q.Which one of the following hormones is secreted by the human placenta that helps in the maintenance of pregnancy? (A) Relaxin (B) Human Chorionic Gonadotropin (C) Oxytocin (D) Human Placental Lactogen
The human placenta secretes Human Chorionic Gonadotropin (hCG), which is crucial for maintaining the corpus luteum and thus the pregnancy in its early stages. The correct option is (B).
The maintenance of pregnancy is a complex process heavily reliant on a delicate balance of hormones. The placenta, a temporary organ formed during pregnancy, plays a central role not only in nutrient and gas exchange but also as a major endocrine gland, producing hormones essential for the continuation of pregnancy and fetal development. Understanding which hormones are produced by the placenta and their specific functions is key to grasping the physiological mechanisms of gestation.
Here's a breakdown of the hormones mentioned and their roles:
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Understanding the Role of the Placenta in Pregnancy Maintenance:
Initially, after ovulation, the corpus luteum (formed from the ruptured follicle in the ovary) produces progesterone and estrogen. These hormones are vital for maintaining the uterine lining (endometrium) and preventing its shedding, which would lead to menstruation and loss of the embryo. If pregnancy occurs, the corpus luteum must be sustained until the placenta is fully developed and can take over hormone production. This is where a specific placental hormone becomes critical.
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Analyzing Option (A) Relaxin:
Relaxin is indeed secreted by the placenta (and also by the corpus luteum). Its primary function is to relax the pelvic ligaments and soften the cervix, particularly towards the end of pregnancy, to facilitate childbirth. While important for the overall process of pregnancy and delivery, its direct role in the maintenance of pregnancy, especially in the early stages to prevent miscarriage, is not as central as other hormones.
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Analyzing Option (B) Human Chorionic Gonadotropin (hCG):
This hormone is secreted by the trophoblast cells of the developing placenta shortly after implantation. Its most critical role in the maintenance of pregnancy is to rescue and sustain the corpus luteum. hCG is structurally similar to Luteinizing Hormone (LH) and binds to LH receptors on the corpus luteum, stimulating it to continue producing progesterone and estrogen. Without hCG, the corpus luteum would degenerate, progesterone levels would drop, and the uterine lining would be shed, leading to menstruation and termination of the pregnancy. This makes hCG absolutely vital for the early maintenance of pregnancy. It is also the hormone detected in pregnancy tests.
ImportanthCG is the primary hormone responsible for maintaining the corpus luteum, which in turn produces progesterone and estrogen to sustain the uterine lining and prevent early pregnancy loss.
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Analyzing Option (C) Oxytocin:
Oxytocin is primarily secreted by the posterior pituitary gland, not the placenta. Its main functions are to stimulate uterine contractions during labor and to promote milk ejection during lactation. While crucial for childbirth, it does not play a role in the maintenance of pregnancy in the sense of preventing its termination.
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Analyzing Option (D) Human Placental Lactogen (hPL) / Chorionic Somatomammotropin:
hPL is secreted by the placenta. Its main functions include modifying the metabolic state of the mother to ensure a continuous supply of glucose and amino acids to the fetus, promoting mammary gland development, and having anti-insulin effects in the mother. While essential for fetal growth and maternal adaptation, its role in the maintenance of pregnancy (i.e., preventing the uterine lining from shedding) is not its primary function.
Considering the specific phrase "helps in the maintenance of pregnancy," especially in the critical early stages, Human Chorionic Gonadotropin (hCG) stands out as the most direct and crucial hormone among the choices provided.
The hormone secreted by the human placenta that helps in the maintenance of pregnancy is (B) Human Chorionic Gonadotropin.
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