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Exercise · Q32

Q.Complete the diagram/chart with correct labels/information and write the conceptual details regarding it: a flow chart with INPUT = 'Low water concentration in blood detected by osmoreceptors in hypothalamus', leading to 'Stimulates release of hypothalamic ADH by posterior pituitary', a blank box, 'Facultative water reabsorption', 'High water concentration in blood', 'Inhibits secretion of _____' (a blank to be filled), and OUTPUT/RETURN TO HOMEOSTASIS = 'Restoration of normal water concentration in blood'. (A related box also notes: 'Na+ transported from proximal convoluted tubules into blood' causes 'higher osmotic pressure in peritubular blood than in filtrate'.) Fill in the blanks and explain the complete pathway.

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Note

As with the previous flowchart, the printed boxes for this exercise were extracted in a scrambled order from a graphic containing at least two linked diagrams (an ADH/osmoreceptor loop and a related Na+/osmotic-pressure box); the sequence below reconstructs the correct logical pathway from section 15.5's own explanation of ADH regulation, rather than the exact box positions on the page.

INPUT: Low water concentration (i.e. high osmolarity) in blood, detected by osmoreceptors in the hypothalamus.

Step 1. This stimulates release of ADH from the posterior pituitary (neurohypophysis).

Step 2 (first blank). ADH increases the permeability of the wall of the collecting duct (and the last part of the DCT) to water.

Step 3. This produces facultative water reabsorption — water moves out of the tubular fluid back into the blood.

Step 4. Blood water concentration is restored to normal (high water concentration in blood) — RETURN TO HOMEOSTASIS.

Step 5 (second blank, 'Inhibits secretion of ____'). Once blood water concentration is back to normal, osmoreceptor activity falls, and this restored state feeds back to inhibit further secretion of ADH — the classic negative-feedback shutoff. …

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