Q.The active chemical drug reserpine is obtained from:
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Start your 14-day free trial to unlock the full solution →The active chemical drug reserpine is obtained from the plant Rauwolfia serpentina.
Reserpine is a significant alkaloid that has profoundly impacted modern medicine, particularly in the treatment of hypertension and as a tranquilizer. Its discovery from a plant traditionally used in indigenous medicine underscores the immense value of biodiversity and ethnobotanical knowledge. Understanding its source is not just about memorizing a fact, but appreciating the journey from traditional remedies to modern pharmaceuticals.
The plant from which reserpine is obtained is Rauwolfia. Specifically, it is derived from Rauwolfia serpentina, commonly known as Sarpagandha or Indian Snakeroot. This plant has a long and rich history in traditional Indian medicine, particularly in Ayurveda.
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Traditional Uses: For centuries, the roots of Rauwolfia serpentina were used in India to treat a variety of ailments. These included snake bites, insect stings, insomnia, and various nervous disorders such as anxiety, agitation, and even certain forms of insanity. Its calming properties were recognized long before modern science identified the active compounds.
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Modern Discovery and Application: In the mid-20th century, scientists successfully isolated reserpine from Rauwolfia serpentina. This isolation marked a pivotal moment in pharmacology. Reserpine became one of the first effective drugs for controlling high blood pressure (hypertension) and was also used as an antipsychotic medication. It works by depleting certain neurotransmitters (like norepinephrine, dopamine, and serotonin) from nerve endings in the brain and peripheral nervous system, leading to a calming effect and a reduction in blood pressure.
Rauwolfia serpentina is a classic example highlighted in NCERT textbooks to illustrate the medicinal value of plants and the importance of biodiversity conservation, as its unique chemical compounds have significant pharmaceutical applications.
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