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Chemistry · Class 12 Science

Ch 10Biomolecules — Class 12 Chemistry, concept-first.

Every living organism grows, maintains itself, and reproduces — yet at bottom it is built from the same non-living atoms and molecules that make up the rest of the physical world.

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Key concepts

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Chapter contents

The NCERT structure, section by section. Open a section to see its questions, then read the concept-first solution.

Introduction

Every living organism grows, maintains itself, and reproduces — yet at bottom it is built from the same non-living atoms and molecules that make up the rest of the physical world.

10.1

Carbohydrates

Carbohydrates form one of the largest groups of naturally occurring organic compounds, and plants are their primary source. Everyday examples include cane sugar, glucose and starch.

10.1.1

Classification of Carbohydrates

Carbohydrates are sorted according to how they behave when hydrolysed — that is, by how many (if any) simpler sugar units they break down into on treatment with acid or water.

10.1.2

Monosaccharides

Within the monosaccharide group itself, a further split is made along two independent axes: how many carbon atoms the molecule has, and which carbonyl functional group it carries.

10.1.2.1

Glucose

Glucose is an aldohexose, and its everyday name in commerce and physiology is dextrose. It occurs freely in nature — sweet fruits, honey and ripe grapes are all rich in it — and also occurs in the com…

10.1.2.2

Fructose

Fructose is the second important hexose sugar of the chapter, and it is a ketohexose rather than an aldohexose.

10.1.3

Disaccharides

When a disaccharide is hydrolysed — using dilute acid or an appropriate enzyme — it splits into two monosaccharide units, which may be identical or different.

10.1.4

Polysaccharides

Polysaccharides are built from a very large number of monosaccharide units, all linked together by glycosidic linkages.

10.1.5

Importance of Carbohydrates

Carbohydrates are essential to life in both the plant and animal kingdoms, forming a major portion of the food that living organisms consume.

10.2

Proteins

Proteins are the single most abundant class of biomolecule in any living system. They are found in every tissue and every part of the body, and they underpin both the structure and the function of lif…

10.2.1

Amino Acids

An amino acid is any molecule carrying two functional groups at once: a basic amino group () and an acidic carboxyl group ().

10.2.2

Classification of Amino Acids

Beyond their individual side chains, amino acids can be grouped into three broad categories based on a simple count: how many amino groups versus how many carboxyl groups a given amino acid's structur…

10.2.3

Structure of Proteins

Proteins are polymers of α-amino acids, and the individual amino acid units are joined to each other through a peptide bond (also called a peptide linkage).

10.2.4

Denaturation of Proteins

A protein that exists in a biological system with its own unique three-dimensional structure and full biological activity is called a native protein.

10.3

Enzymes

A living organism survives because thousands of chemical reactions inside it run in a coordinated sequence — digesting food, absorbing the useful molecules, and finally releasing energy from them is o…

10.3.1

Mechanism of Enzyme Action

Because an enzyme acts as a catalyst and is not itself consumed in the reaction it speeds up, a reaction can be driven to completion using only a tiny quantity of the enzyme relative to the amount of…

10.4

Vitamins

Certain organic compounds are needed by the body only in very small quantities, yet their absence has a very specific consequence: a deficiency of one particular vitamin produces one particular diseas…

10.4.1

Classification of Vitamins

Vitamins are sorted into two broad groups purely on the basis of one physical property: whether they dissolve in water or in fat.

10.5

Nucleic Acids

Every organism resembles its parents and ancestors in many ways — this transmission of inherited characters from one generation to the next is called heredity.

10.5.1

Chemical Composition of Nucleic Acids

When a nucleic acid (DNA or RNA) is completely hydrolysed, it breaks down into three distinct types of simpler molecules:

10.5.2

Structure of Nucleic Acids

The first step in assembling a nucleic acid is attaching a base to the sugar. A base is linked to the position of the pentose sugar through a β-N-glycosidic linkage (the base's nitrogen bonds to the a…

10.5.3

Biological Functions of Nucleic Acids

DNA is the chemical basis of heredity — it can be thought of as the cell's permanent reserve of genetic information.

10.6

Hormones

Hormones are molecules that carry signals between cells, allowing one part of the body to instruct another.

Summary

- Carbohydrates: Polyhydroxy aldehydes or ketones. Classified as monosaccharides (e.g., glucose ), oligosaccharides (e.g., sucrose), and polysaccharides (e.g., starch, cellulose).

Exercises

+Show 25 questions25 questions
  1. 10.1What are monosaccharides?Free
  2. 10.2What are reducing sugars?Free
  3. 10.3Write two main functions of carbohydrates in plants.Free
  4. 10.4Classify the following into monosaccharides and disaccharides. Ribose, 2-deoxyribose, maltose, galactose, fructose and lactose.Preview
  5. 10.5What do you understand by the term glycosidic linkage?Preview
  6. 10.6What is glycogen? How is it different from starch?Preview
  7. 10.7What are the hydrolysis products of (i) sucrose and (ii) lactose?Preview
  8. 10.8What is the basic structural difference between starch and cellulose?Preview
  9. 10.9What happens when D-glucose is treated with the following reagents? (i) $HI$ (ii) Bromine water (iii) $HNO_3$Preview
  10. 10.10Enumerate the reactions of D-glucose which cannot be explained by its open chain structure.Preview
  11. 10.11What are essential and non-essential amino acids? Give two examples of each type.Preview
  12. 10.12Define the following as related to proteins: (i) Peptide linkage (ii) Primary structure (iii) DenaturationPreview
  13. 10.13What are the common types of secondary structure of proteins?Preview
  14. 10.14What type of bonding helps in stabilising the $\alpha$-helix structure of proteins?Preview
  15. 10.15Differentiate between globular and fibrous proteins.Preview
  16. 10.16How do you explain the amphoteric behaviour of amino acids?Preview
  17. 10.17What are enzymes?Preview
  18. 10.18What is the effect of denaturation on the structure of proteins?Preview
  19. 10.19How are vitamins classified? Name the vitamin responsible for the coagulation of blood.Preview
  20. 10.20Why are vitamin A and vitamin C essential to us? Give their important sources.Preview
  21. 10.21What are nucleic acids? Mention their two important functions.Preview
  22. 10.22What is the difference between a nucleoside and a nucleotide?Preview
  23. 10.23The two strands in DNA are not identical but are complementary. Explain.Preview
  24. 10.24Write the important structural and functional differences between DNA and RNA.Preview
  25. 10.25What are the different types of RNA found in the cell?Preview

Answers to Intext Questions

These are the final answers printed at the end of the NCERT chapter. The book gives answers for some intext questions only — every question below links to our complete worked solution.

Exemplar Problems

Higher-order thinking / exemplar-style practice problems.

+Show 71 questions71 questions
  1. Q1Glycogen is a branched chain polymer of $\alpha$-D-glucose units in which chain is formed by C1-C4 glycosidic linkage whereas branching occu…Free
  2. Q2Which of the following polymers is stored in the liver of animals? (i) Amylose (ii) Cellulose (iii) Amylopectin (iv) GlycogenFree
  3. Q3Sucrose (cane sugar) is a disaccharide. One molecule of sucrose on hydrolysis gives _______. (i) 2 molecules of glucose (ii) 2 molecules of…Free
  4. Q4Anomers are two cyclic forms of the same monosaccharide that differ in configuration only at the anomeric carbon (the carbon that was the ca…Preview
  5. Q5Proteins are found to have two different types of secondary structures viz. $\alpha$-helix and $\beta$-pleated sheet structure. $\alpha$-hel…Preview
  6. Q6In a disaccharide, if the reducing groups (the aldehydic or ketonic/anomeric carbons) of BOTH monosaccharide units are used up in the glycos…Preview
  7. Q7Which of the following acids is a vitamin? (i) Aspartic acid (ii) Ascorbic acid (iii) Adipic acid (iv) Saccharic acidPreview
  8. Q8Dinucleotide is obtained by joining two nucleotides together by phosphodiester linkage. Between which carbon atoms of pentose sugars of nucl…Preview
  9. Q9Nucleic acids are the polymers of _______. (i) nucleosides (ii) nucleotides (iii) bases (iv) sugarsPreview
  10. Q10Which of the following statements is not true about glucose? (i) It is an aldohexose. (ii) On heating with HI it forms n-hexane. (iii) It is…Preview
  11. Q11Each polypeptide in a protein has amino acids linked with each other in a specific sequence. This sequence of amino acids is said to be ____…Preview
  12. Q12DNA and RNA contain four bases each. Which of the following bases is not present in RNA? (i) Adenine (ii) Uracil (iii) Thymine (iv) CytosinePreview
  13. Q13Which of the following B group vitamins can be stored in our body? (i) Vitamin B$_1$ (ii) Vitamin B$_2$ (iii) Vitamin B$_6$ (iv) Vitamin B$_…Preview
  14. Q14Which of the following bases is not present in DNA? (i) Adenine (ii) Thymine (iii) Cytosine (iv) UracilPreview
  15. Q15Three cyclic monosaccharide structures (labelled I, II and III) are drawn as Fischer projections closed by a ring oxygen, each ending in a C…Preview
  16. Q16Which of the following reactions of glucose can be explained only by its cyclic structure? (i) Glucose forms pentaacetate. (ii) Glucose reac…Preview
  17. Q17The prefixes D and L denote the configuration of the highest-numbered chiral carbon of a sugar (the chiral carbon nearest the terminal CH2OH…Preview
  18. Q18The disaccharide sucrose is formed from a glucose unit and a fructose unit. In the given structure the six carbons of the glucose ring are l…Preview
  19. Q19Three structures, labelled (A), (B) and (C), each show two glucose units joined by a glycosidic oxygen. In structure (A) the two six-membere…Preview
  20. Q20Name the sugar present in milk. How many monosaccharide units are present in it? What are such oligosaccharides called?Preview
  21. Q21How do you explain the presence of all the six carbon atoms in glucose in a straight chain?Preview
  22. Q22In nucleoside, a base is attached at the 1' position of the sugar moiety. Nucleotide is formed by linking of phosphoric acid unit to the sug…Preview
  23. Q23Name the linkage connecting monosaccharide units in polysaccharides.Preview
  24. Q24Under what conditions glucose is converted to gluconic and saccharic acid?Preview
  25. Q25Monosaccharides contain carbonyl group hence are classified as aldose or ketose. The number of carbon atoms present in the monosaccharide mo…Preview
  26. Q26The prefixes 'D' and 'L' before a sugar's name give the configuration of its reference carbon - the highest-numbered chiral carbon, i.e. the…Preview
  27. Q27Aldopentoses named ribose and 2-deoxyribose are found in nucleic acids. What is their relative configuration?Preview
  28. Q28Which sugar is called invert sugar? Why is it called so?Preview
  29. Q29Amino acids can be classified as $\alpha$-, $\beta$-, $\gamma$-, $\delta$- and so on depending upon the relative position of the amino group…Preview
  30. Q30$\alpha$-Helix is a secondary structure of proteins formed by twisting of polypeptide chain into right handed screw like structures. Which t…Preview
  31. Q31Some enzymes are named after the reaction, where they are used. What name is given to the class of enzymes which catalyse the oxidation of o…Preview
  32. Q32During curdling of milk, what happens to sugar present in it?Preview
  33. Q33How do you explain the presence of five —OH groups in glucose molecule?Preview
  34. Q34Consider compound (A): a cyclic (pyranose) form of glucose, drawn as a Fischer-type projection closed into a ring by an oxygen that joins th…Preview
  35. Q35Why must vitamin C be supplied regularly in diet?Preview
  36. Q36Sucrose is dextrorotatory but the mixture obtained after hydrolysis is laevorotatory. Explain.Preview
  37. Q37Amino acids behave like salts rather than simple amines or carboxylic acids. Explain.Preview
  38. Q38Structures of glycine and alanine are given below. Show the peptide linkage in glycylalanine.Preview
  39. Q39Protein found in a biological system with a unique three dimensional structure and biological activity is called a native protein. When a pr…Preview
  40. Q40The activation energy for the acid catalysed hydrolysis of sucrose is 6.22 kJ mol$^{-1}$, while the activation energy is only 2.15 kJ mol$^{…Preview
  41. Q41How do you explain the presence of an aldehydic group in a glucose molecule?Preview
  42. Q42Which moieties of nucleosides are involved in the formation of phosphodiester linkages present in dinucleotides? What does the word diester…Preview
  43. Q43What are glycosidic linkages? In which type of biomolecules are they present?Preview
  44. Q44Which monosaccharide units are present in starch, cellulose and glycogen and which linkages link these units?Preview
  45. Q45How do enzymes help a substrate to be attacked by the reagent effectively?Preview
  46. Q46Describe the term D- and L-configuration used for amino acids with examples.Preview
  47. Q47How will you distinguish 1° and 2° hydroxyl groups present in glucose? Explain with reactions.Preview
  48. Q48Coagulation of egg white on boiling is an example of denaturation of protein. Explain it in terms of structural changes.Preview
  49. Q49Write the reactions of D-glucose which cannot be explained by its open chain structure. How can cyclic structure of glucose explain these re…Preview
  50. Q50On the basis of which evidences D-glucose was assigned the following structure (the open chain structure of D-glucose)?Preview
  51. Q51Carbohydrates are essential for life in both plants and animals. Name the carbohydrates that are used as storage molecules in plants and ani…Preview
  52. Q52Explain the terms primary and secondary structure of proteins. What is the difference between $\alpha$-helix and $\beta$-pleated sheet struc…Preview
  53. Q53Write the structures of fragments produced on complete hydrolysis of DNA. How are they linked in DNA molecule? Draw a diagram to show pairin…Preview
  54. Q54Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing sugar. Sucrose is a _______.…Preview
  55. Q55Proteins can be classified into two types on the basis of their molecular shape i.e., fibrous proteins and globular proteins. Examples of gl…Preview
  56. Q56Which of the following carbohydrates are branched polymer of glucose? (Note: one or more of the following options may be correct.) (i) Amylo…Preview
  57. Q57Amino acids are classified as acidic, basic or neutral according to the relative number of amino (-NH2) and carboxyl (-COOH) groups they con…Preview
  58. Q58Lysine, $\text{H}_2\text{N}(\text{CH}_2)_4\text{CH}(\text{NH}_2)\text{COOH}$, is _______. (Note: one or more of the following options may be…Preview
  59. Q59Which of the following monosaccharides are present as five membered cyclic structure (furanose structure)? (Note: one or more of the followi…Preview
  60. Q60In fibrous proteins, polypeptide chains are held together by _______. (Note: one or more of the following options may be correct.) (i) van d…Preview
  61. Q61Which of the following are purine bases? (Note: one or more of the following options may be correct.) (i) Guanine (ii) Adenine (iii) Thymine…Preview
  62. Q62Which of the following terms are correct about enzymes? (Note: one or more of the following options may be correct.) (i) Proteins (ii) Dinuc…Preview
  63. Q63Match the vitamins given in Column I with the deficiency disease they cause given in Column II. Column I (Vitamins): (A) Vitamin A; (B) Vita…Preview
  64. Q64Match the following enzymes given in Column I with the reactions they catalyse given in Column II. Column I (Enzymes): (A) Invertase; (B) Ma…Preview
  65. Q65Assertion (A): D(+)-Glucose is dextrorotatory in nature. Reason (R): 'D' represents its dextrorotatory nature. (i) Both A and R are true and…Preview
  66. Q66Assertion (A): Vitamin D can be stored in our body. Reason (R): Vitamin D is a fat soluble vitamin. (i) Both A and R are true and R is the c…Preview
  67. Q67Assertion (A): $\beta$-glycosidic linkage is present in maltose. Reason (R): Maltose is composed of two glucose units in which C-1 of one gl…Preview
  68. Q68Assertion (A): All naturally occurring $\alpha$-amino acids except glycine are optically active. Reason (R): Most naturally occurring amino…Preview
  69. Q69Assertion (A): Deoxyribose, $\text{C}_5\text{H}_{10}\text{O}_4$ is not a carbohydrate. Reason (R): Carbohydrates are hydrates of carbon so c…Preview
  70. Q70Assertion (A): Glycine must be taken through diet. Reason (R): It is an essential amino acid. (i) Both A and R are true and R is the correct…Preview
  71. Q71Assertion (A): In presence of enzyme, substrate molecule can be attacked by the reagent effectively. Reason (R): Active sites of enzymes hol…Preview

Sample & Board Papers

Sample papers and previous-year board questions for this subject.