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Question 49 of 56

Q.Draw the different types of human WBC.

Tamil Nadu DgeTamil Nadu HSC First Year (DGE) Board 2025Subjective· 3mImportance★★★★★
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Figure — Five human leukocytes drawn and labelled as rounded cells with correct nucleus and granules
Figure — Five human leukocytes drawn and labelled as rounded cells with correct nucleus and granules

Human WBCs (leukocytes) are of five types, divided into granulocytes (Neutrophils, Eosinophils, Basophils) and agranulocytes (Lymphocytes, Monocytes); a hand-drawn figure isn't possible in this format, so each type's defining shape and staining features are described here for you to sketch and label yourself.

White blood cells are classified based on whether their cytoplasm shows visible granules under the microscope after staining:

Granulocytes (granular cytoplasm, lobed nucleus):

  1. Neutrophils: the most abundant WBC; nucleus has 2-5 lobes connected by thin strands (polymorphonuclear); cytoplasm shows fine, pale (neutral-staining) granules. Function: phagocytose bacteria, first responders in infection.
  2. Eosinophils: nucleus typically bilobed; cytoplasm packed with large, coarse granules that stain reddish-orange with eosin. Function: combat parasitic infections and involved in allergic responses.
  3. Basophils: least abundant WBC; nucleus is bilobed but often obscured by very large, coarse granules that stain dark blue-purple with basic dyes. Function: release histamine and heparin, involved in inflammatory/allergic responses.

Agranulocytes (no visible granules, rounder nucleus):

4. Lymphocytes: small to medium cells with a large, round, densely-stained nucleus that fills most of the cell, leaving only a thin rim of clear cytoplasm. Function: B-lymphocytes (antibody production) and T-lymphocytes (cell-mediated immunity). …

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