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Evaluation · Q18

Q.Write the causes for diabetes mellitus and diabetes insipidus.

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Step 1. Diabetes mellitus (hyperglycaemia) is caused by reduced insulin secretion, so blood glucose is not taken up by cells and remains elevated.

Step 2. It has two distinct causes: Type I diabetes (insulin-dependent) is caused by an actual lack of insulin secretion, often triggered by illness or viral infection; Type II diabetes (non-insulin-dependent) is caused by reduced tissue sensitivity to the insulin present, known as insulin resistance.

Step 3. Diabetes insipidus is an entirely different disorder involving a different hormone and gland: it is caused by hyposecretion of vasopressin (antidiuretic hormone, ADH) from the neurohypophysis (posterior pituitary). …

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