Why do you think it is not possible to produce vaccine against 'common cold'?

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Q. Why do you think it is not possible to produce vaccine against 'common cold'?

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Step 1. The chapter identifies rhinoviruses as the cause of the common cold, describing it as one of the most infectious human ailments.

Step 2. A vaccine works by training the immune system to recognize a specific pathogen's surface markers; it protects well when a disease is caused by one, or a few, stable strains (as with several diseases in this chapter successfully controlled by vaccines, such as polio, diphtheria and tetanus).

Step 3. Rhinoviruses, however, exist as a very large number of distinct serotypes, and they also change/mutate readily. Immunity built against one strain therefore offers little to no protection against the many other circulating strains, and a new strain can still cause a cold even in someone previously infected. …

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Same / Similar Concept — real previous-year questions on the same or a closely similar concept, not this exact question.

CBSE 2019Set ANNUAL1 markMCQ
$Q. HIV is a member of the sub-family ________.$
(a) Rhabdovirus
(b) Pencillia
(c) Vaccinia
(d) Lentivirinae
›Reveal solutionSolution

HIV belongs to the Lentivirinae, the 'slow virus' subfamily of retroviruses.

HIV (Human Immunodeficiency Virus) is a member of the Retroviridae family and, within it, the Lentivirinae subfamily — lentiviruses cause slowly progressing, long-latency infections, matching HIV's typically years-long asymptomatic period before AIDS develops. Rhabdovirus (e.g., rabies virus) and Vaccinia virus (used in smallpox vaccines) …

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CBSE 2018Set ANNUAL1 markMCQ
$Q. The most promising chemotherapeutic agent for treating viral disease is:$
(a) Interferon
(b) Tetracycline
(c) Anthramycin
(d) Ampicillin
›Reveal solutionSolution

Interferon is the most promising chemotherapeutic agent for viral diseases.

Interferons are proteins released by virus-infected cells that make neighbouring cells resistant to viral multiplication. Because viruses replicate inside host cells, antibacterial antibiotics are ineffective against them, so interferon (which specifically blocks viral replication) is the promising antiviral agent.

…

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CBSE 2016Set ANNUAL1 markMCQ
$Q. Which converts RNA genome into DNA in HIV ?$
(a) DNA ligase
(b) Restriction endonuclease
(c) Reverse transcriptase
(d) DNA polymerase
›Reveal solutionSolution

Reverse transcriptase is the retroviral enzyme HIV uses to convert its RNA genome into DNA.

As a retrovirus, HIV carries reverse transcriptase inside its virion; after entering a host T-helper cell, this enzyme synthesises a DNA copy from the viral RNA template, and this proviral DNA integrates into the host genome, letting the virus hijack the cell's machinery. DNA ligase joins DNA fragments, restriction endonucleases cut DNA at specific sites, …

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Q.Why do you think it is not possible to produce vaccine against 'common cold'?

Concept understanding — Viral Diseases in Humans

Q.Why do you think it is not possible to produce vaccine against 'common cold'?

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