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Short Answer Questions · Q19

Q.Explain the mechanism of inspiration in humans, with reference to the diaphragm, the external intercostal muscles, and the resulting change in pulmonary pressure.

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Inspiration begins when the diaphragm contracts, pulling its dome downward and increasing the vertical dimension of the thoracic cavity, while at nearly the same moment the external intercostal muscles contract, pulling the ribs upward and outward and increasing the front-to-back and side-to-side dimensions as well. Because the lungs are elastic and mechanically coupled to the thoracic wall via the pleural membranes, this enlargement of the thoracic cavity is transmitted to the lungs, increasing pulmonary volume. By the inverse pressure-volume relationship of an enclosed gas, this increase in pulmonary volume lowers pulmonary pressure to slightly below atmospheric pressure, and air flows in from the higher-pressure atmosphere down this gradient until the pressures equalise, completing inspiration.

[!ANSWER]

Diaphragm contracts and flattens; external intercostal muscles contract, pulling ribs up and out; thoracic volume increases; pulmonary pressure falls below atmospheric; air flows in.

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